Results 1 to 10 of about 288,034 (253)
Frontiers in Molecular Neuroscience – Résumé and Perspective [PDF]
Frontiers in Molecular Neuroscience, 2011 The open access journal Frontiers in Molecular Neuroscience has existed since 2008. Publications started with an inaugural Research Topic centered on molecular mechanisms of the regulation of excitatory and inhibitory synapses in the brain – also known as E–I balance.
Jochen C Meier +2 more
exaly +5 more sources
The emergence of molecular systems neuroscience [PDF]
Molecular Brain, 2022 AbstractSystems neuroscience is focused on how ensemble properties in the brain, such as the activity of neuronal circuits, gives rise to internal brain states and behavior. Many of the studies in this field have traditionally involved electrophysiological recordings and computational approaches that attempt to decode how the brain transforms inputs ...
Shen, Yang +4 more
openaire +6 more sources
Molecular neuroscience: challenges ahead. [PDF]
Front Neurosci, 2008 A molecular neuroscientist with a pessimistic bent might feel that his field is coming to a close, seeing that most molecules contributing to a neuron's well-being and functional states are now known to us. There will still be unexplored ion channels and transcription factors in our genome, but isn't it merely a matter of time before these will be ...
Seeburg PH.
europepmc +5 more sources
Editorial overview: Molecular neuroscience. [PDF]
Curr Opin Neurobiol, 2019 Ryan TA, Jin Y.
europepmc +4 more sources
Editorial: Women in molecular neuroscience. [PDF]
Front Mol NeurosciŽerovnik E.
europepmc +4 more sources
Molecular and Functional Neuroscience in Immunity [PDF]
Annual Review of Immunology, 2018 The nervous system regulates immunity and inflammation. The molecular detection of pathogen fragments, cytokines, and other immune molecules by sensory neurons generates immunoregulatory responses through efferent autonomic neuron signaling. The functional organization of this neural control is based on principles of reflex regulation.
Valentin A, Pavlov +2 more
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Neuroscience of alcoholism: molecular and cellular mechanisms [PDF]
Cellular and Molecular Life Sciences, 2009 Alcohol use and abuse appear to be related to neuroadaptive changes at functional, neurochemical, and structural levels. Acute and chronic ethanol exposure have been shown to modulate function of the activity-dependent gene transcription factor, cAMP-responsive element binding (CREB) protein in the brain, which may be associated with the development of
Sachin, Moonat +3 more
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Aptamers as Valuable Molecular Tools in Neurosciences [PDF]
The Journal of Neuroscience, 2017 Aptamers are short nucleic acids that interact with a variety of targets with high affinity and specificity. They have been shown to inhibit biological functions of cognate target proteins, and they are identifiable by anin vitroselection process, also termed SELEX (Systematic Evolution of Ligands by EXponential enrichment).
Olga, Wolter, Günter, Mayer
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source