Results 1 to 10 of about 431,157 (128)

In vitro cell models merging circadian rhythms and brain waves for personalized neuromedicine

open access: yesiScience, 2022
Summary: New evidence is emerging about the dynamics of interaction between circadian rhythms and brain waves, whose coordination occurs through the entrainment process.
Barbara Pavan, Anna Bianchi, Giada Botti
doaj   +1 more source

Tonic activin signaling shapes cellular and synaptic properties of CA1 neurons mainly in dorsal hippocampus

open access: yesiScience, 2023
Summary: Dorsal and ventral hippocampus serve different functions in cognition and affective behavior, but the underpinnings of this diversity at the cellular and synaptic level are not well understood.
Marc Dahlmanns   +4 more
doaj   +1 more source

Heterogeneity of intrinsic plasticity in cerebellar Purkinje cells linked with cortical molecular zones

open access: yesiScience, 2022
Summary: In the cerebellar cortex, heterogeneous populations of Purkinje cells (PCs), classified into zebrin (aldolase C)-positive (Z+) and -negative (Z-) types, are arranged into separate longitudinal zones.
Nguyen-Minh Viet   +3 more
doaj   +1 more source

Muscarinic acetylcholine receptor-dependent and NMDA receptor-dependent LTP and LTD share the common AMPAR trafficking pathway

open access: yesiScience, 2023
Summary: The forebrain cholinergic system promotes higher brain function in part by signaling through the M1 muscarinic acetylcholine receptor (mAChR). Long-term potentiation (LTP) and long-term depression (LTD) of excitatory synaptic transmission in the
Tomonari Sumi, Kouji Harada
doaj   +1 more source

Differential recruitment of ventral pallidal e-types by behaviorally salient stimuli during Pavlovian conditioning

open access: yesiScience, 2021
Summary: The ventral pallidum (VP) is interfacing striatopallidal and limbic circuits, conveying information about salience and valence crucial to adjusting behavior.
Panna Hegedüs   +2 more
doaj   +1 more source

Remote cortical perturbation dynamically changes the network solutions to given tactile inputs in neocortical neurons

open access: yesiScience, 2022
Summary: The neocortex has a globally encompassing network structure, which for each given input constrains the possible combinations of neuronal activations across it. Hence, its network contains solutions.
Leila Etemadi   +2 more
doaj   +1 more source

Glucokinase neurons of the paraventricular nucleus of the thalamus sense glucose and decrease food consumption

open access: yesiScience, 2021
Summary: The paraventricular nucleus of the thalamus (PVT) controls goal-oriented behavior through its connections to the nucleus accumbens (NAc). We previously characterized Glut2aPVT neurons that are activated by hypoglycemia, and which increase ...
Sébastien Kessler   +5 more
doaj   +1 more source

Intracellular Ca2+ dynamics in the ALA neuron reflect sleep pressure and regulate sleep in Caenorhabditis elegans

open access: yesiScience, 2022
Summary: The mechanisms underlying sleep homeostasis are poorly understood. The nematode Caenorhabditis elegans exhibits 2 types of sleep: lethargus, or developmentally timed, and stress-induced sleep.
Shinichi Miyazaki   +3 more
doaj   +1 more source

Anatomical organization of temporally correlated neural calcium activity in the hippocampal CA1 region

open access: yesiScience, 2023
Summary: Hippocampal CA1 neuronal ensembles generate sequential patterns of firing activity that contribute to episodic memory formation and spatial cognition. Here we used in vivo calcium imaging to record neural ensemble activities in mouse hippocampal
Lujia Chen   +6 more
doaj   +1 more source

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