Results 31 to 40 of about 431,276 (246)
iScience, 2023 Summary: The organization of fear memory involves the participation of multiple brain regions. However, it is largely unknown how fear memory is formed, which circuit pathways are used for “printing” memory engrams across brain regions, and the role of ...
Ilaria Bertocchi +14 more
doaj +1 more source
Knowing one's place: a free-energy approach to pattern regulation. [PDF]
, 2015 Understanding how organisms establish their form during embryogenesis and regeneration represents a major knowledge gap in biological pattern formation.
Friston, K +3 more
core +1 more source
iScience, 2020 Summary: The microtubule-associated tau protein forms pathological inclusions that accumulate in an age-dependent manner in tauopathies including Alzheimer's disease (AD). Since age is the major risk factor for AD, we examined endogenous tau species that
Connor M. Wander +11 more
doaj +1 more source
Isolation and Characterization of Ischemia-Derived Astrocytes (IDAs) with Ability to Transactivate Quiescent Astrocytes [PDF]
, 2016 Reactive gliosis involving activation and proliferation of astrocytes and microglia, is a widespread but largely complex and graded glial response to brain injury.
Barbeito, Osvaldo Luis +8 more
core +1 more source
iScience, 2023 Summary: The death-associated protein kinase 1 (DAPK1) regulates the synaptic movement of the Ca2+/calmodulin (CaM)-dependent protein kinase II (CaMKII).
Jonathan E. Tullis, K. Ulrich Bayer
doaj +1 more source
3D Ultrastructure of the Cochlear Outer Hair Cell Lateral Wall Revealed By Electron Tomography. [PDF]
, 2019 Outer Hair Cells (OHCs) in the mammalian cochlea display a unique type of voltage-induced mechanical movement termed electromotility, which amplifies auditory signals and contributes to the sensitivity and frequency selectivity of mammalian hearing ...
Auer, Manfred +6 more
core +3 more sources
Galectin-3-mediated glial crosstalk drives oligodendrocyte differentiation and (Re)myelination [PDF]
, 2018 Galectin-3 (Gal-3) is the only chimeric protein in the galectin family. Gal-3 structure comprises unusual tandem repeats of proline and glycine-rich short stretches bound to a carbohydrate-recognition domain (CRD).
Pasquini, Laura Andrea, Thomas, Laura
core +1 more source
Substantia nigra modulates breathing rate via locus coeruleus
iScienceSummary: Breathing is an automatic and rhythmic act primarily controlled by hindbrain neural circuits, including the pre-Bötzinger complex. While the basal ganglia are known to regulate a wide range of behaviors through downstream projections, their role
Bon-Mi Gu +4 more
doaj +1 more source
The endocannabinoid/cannabinoid receptor 2 system protects against cisplatin-induced hearing loss [PDF]
, 2018 Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell culture model, it was also shown that an agonist of the CB2R protected these cells ...
Asmita Dhukhwa +8 more
core +4 more sources
Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease [PDF]
, 2018 The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role of peripheral inflammation induced by systemic lipopolysaccharide (LPS) administration in the MPTP-based model of Parkinson’s ...
Carrillo Jiménez, Alejandro +7 more
core +3 more sources