Results 11 to 20 of about 3,929,505 (299)

The temporal pattern of synaptic activation determines the longevity of structural plasticity at dendritic spines

iScience, 2023
Summary: Learning is thought to involve physiological and structural changes at individual synapses. Synaptic plasticity has predominantly been studied using regular stimulation patterns, but neuronal activity in the brain normally follows a Poisson ...
Ali Özgür Argunsah, Inbal Israely
doaj   +1 more source

Molecular and Functional Neuroscience in Immunity [PDF]

Annual Review of Immunology, 2018
The nervous system regulates immunity and inflammation. The molecular detection of pathogen fragments, cytokines, and other immune molecules by sensory neurons generates immunoregulatory responses through efferent autonomic neuron signaling. The functional organization of this neural control is based on principles of reflex regulation.
Valentin A, Pavlov, Sangeeta S, Chavan, Kevin J, Tracey   +2 more
openaire   +2 more sources

Structural basis for SARM1 inhibition and activation under energetic stress

eLife, 2020
SARM1, an executor of axonal degeneration, displays NADase activity that depletes the key cellular metabolite, NAD+, in response to nerve injury. The basis of SARM1 inhibition and its activation under stress conditions are still unknown. Here, we present
Michael Sporny, Julia Guez-Haddad, Tami Khazma, Avraham Yaron, Moshe Dessau, Yoel Shkolnisky, Carsten Mim, Michail N Isupov, Ran Zalk, Michael Hons, Yarden Opatowsky   +10 more
doaj   +1 more source

m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs

iScience, 2022
Summary: m6A modification plays an important role in regulating mammalian neurogenesis. However, whether and how the major cytoplasmic m6A readers, YTHDF1, YTHDF2, and YTHDF3 mediate this process is still not clear.
Fugui Niu, Pengfei Che, Zhuoxuan Yang, Jian Zhang, Lixin Yang, Mengru Zhuang, Xijun Ou, Sheng-Jian Ji   +7 more
doaj   +1 more source

Molecular psychiatry of zebrafish [PDF]

, 2014
Due to their well-characterized neural development and high genetic homology to mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field of biological psychiatry.
Parker, M. O., Stewart, AM, Stewart, A. M., Stewart, A. M ., Ullmann, J. F. P., Norton, WHJ, Ullmann, JFP, Kalueff, A. V., Gerlai, R, Norton, W. H. J., Brennan, C. H., Gerlai, R., Brennan, CH, Parker, MO, Kalueff, AV   +14 more
core   +1 more source

Mu-opioid receptor selective superagonists produce prolonged respiratory depression

iScience, 2023
Summary: Synthetic opioids are increasingly challenging to combat the opioid epidemic and act primarily at opioid receptors, chiefly the G protein-coupled receptor (GPCR) μ-opioid receptor (MOR), which signals through G protein-dependent and β-arrestin ...
Nicholas J. Malcolm, Barbara Palkovic, Daniel J. Sprague, Maggie M. Calkins, Janelle K. Lanham, Adam L. Halberstadt, Astrid G. Stucke, John D. McCorvy   +7 more
doaj   +1 more source

Behavioral observation of xenopus tadpole swimming for neuroscience labs [PDF]

, 2014
Neuroscience labs benefit from reliable, easily - monitored neural responses mediated by well - studied neural pathways . Xenopus laevis tadpoles have been used as a simple vertebrate model preparation in motor control studies.
Porter, Nicola Jean, Li, Wenchang, Wagner, Monica Anne   +2 more
core   +2 more sources

Welcome to Molecular Brain [PDF]

, 2008
We are delighted to announce the arrival of a brand new journal dedicated to the ever-expanding field of neuroscience. Molecular Brain is a peer-reviewed, open-access online journal that aims at publishing high quality articles as rapidly as possible ...
Lee C Justin, C Justin Lee, Lin Mei, Li, Xiao-Jiang, Xiao-Jiang Li, Kaang, Bong-Kiun, Bong-Kiun Kaang, Li Xiao-Jiang, Cho, Kei, Lee, C J, Lin Mei, Kaang Bong-Kiun, Mei Lin, Mei, Lin, Cho Kei, Kei Cho, Min Zhuo, Zhuo Min, Zhuo, Min, Lee, C Justin   +19 more
core   +1 more source

Neuroscience Needs Network Science [PDF]

, 2023
The brain is a complex system comprising a myriad of interacting neurons, posing significant challenges in understanding its structure, function, and dynamics.
Bullmore, E, Sporns, O, Kovács, IA, Hernán Makse, Christos Papadimitriou, Albert-László Barabási, György Buzsáki, Hongkui Zeng, Bianconi, G, Ed Bullmore, Zador, AM, Tina Eliassi-Rad, Thomas E. Nichols, Towlson, EK, Zeng, H, Anthony M. Zador, Buzsáki, G, Kim Stachenfeld, Burgess, M, Nichols, TE, Olaf Sporns, Amy Bernard, Barabási, DL, Dileep George, Emma K. Towlson, Bernard, A, Stachenfeld, K, Mark Burgess, SueYeon Chung, Zoltán Toroczkai, Chung, S, Dániel L. Barabási, George, D, Ginestra Bianconi, Eliassi-Rad, T, István A. Kovács, Makse, H, Barabási, A-L, Toroczkai, Z, Papadimitriou, C, Chung, Sue Yeon, Kovács, István A., Papadimitriou, Christos, Zador, Anthony M., Makse, Hernán, Stachenfeld, Kim, Bianconi, Ginestra, Zeng, Hongkui, Nichols, Thomas E., Bullmore, Ed, Bernard, Amy, Eliassi-Rad, Tina, Burgess, Mark, Sporns, Olaf, Barabási, Dániel L., George, Dileep, Toroczkai, Zoltán, Buzsáki, György, Barabási, Albert László, Towlson, Emma K.   +59 more
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Miami Neuroscience Institute - Winter 2021

, 2021
https://scholarlycommons.baptisthealth.net/bg-bh-neuroscience-news/1004/thumbnail ...
Miami Neuroscience Institute
core   +1 more source