Results 171 to 180 of about 3,939,990 (297)

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Molecular cloning and defence functional analysis of <i>MaNPR11</i> from Cavendish banana (<i>Musa</i> spp.). [PDF]

Front Plant Sci
Wang JY, Wang X, Jia CH, Zhu ML, Lv YY, Wang Z.   +5 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Molecular Cloning and Functional Characterization of Δ9 Fatty Acyl Desaturase in <i>Scylla paramamosain</i>: Insights into Its Regulatory Roles Under Salinity Challenge, Dietary Fatty Acid Alteration and Starvation Stress. [PDF]

Life (Basel)
Lin Z, Sun Z, Chen Y, Li C, Chen R, Han K, Huang W.   +6 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Molecular cloning and characterization of a GH10 thermophilic xylanase from hot spring and its potential application in promoting probiotic growth. [PDF]

BMC Biotechnol
Li JL, Hu W, Pu LH, Sun J, Ortúzar M, Lv ZH, Yang ZF, Zhu D, Xie KQ, Yang LQ, Yin YR.   +10 more
europepmc   +1 more source

Molecular Cloning and Functional Characterization of the 5' Regulatory Region of the SLC11A1 Gene from Yaks. [PDF]

Animals (Basel), 2023
Chong Y, Wang L, Wang B, Gao Z, Lu Y, Deng W, Xi D.   +6 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Molecular cloning and characterization of duck CD83 and its effect on H9N2 avian influenza virus replication. [PDF]

Poult Sci
Li H, Xin X, Yin Z, Dong C, Li F, Liu Y, Kong X, Wang L, Wang J, Yu F, Huo S.   +10 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source