Results 251 to 260 of about 3,546,850 (294)

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang   +7 more
wiley   +1 more source

Hydrodynamic Selection of Polymorphic Assembly Pathways in Plant Protein Amyloid Fibrils

open access: yesAdvanced Science, EarlyView.
Hydrodynamic conditions are revealed to govern polymorphic assembly of soy protein amyloid fibrils. Distinct flow‐induced drafting, kissing, and docking dynamics direct fibril growth into multiple morphologies, linking fluid mechanics with nanoscale assembly and enabling rational design of functional amyloid materials.
Zejian Xu   +8 more
wiley   +1 more source

Origin, evolution, and fate of Titan's polar clouds. [PDF]

open access: yesNat Commun
de Batz de Trenquelléon B   +3 more
europepmc   +1 more source

Testing a Potential Averaging for Quantum Inelastic Dynamics. [PDF]

open access: yesJ Phys Chem A
Giri K   +6 more
europepmc   +1 more source

Interstellar Molecular Clouds

Science, 1986
The interstellar medium in our galaxy contains matter in a variety of states ranging from hot plasma to cold and dusty molecular gas. The molecular phase consists of giant clouds, which are the largest gravitationally bound objects in the galaxy, the primary reservoir of material for the ongoing birth of new stars, and the medium regulating the ...
openaire   +2 more sources

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