Results 71 to 80 of about 4,469,999 (359)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Turbulence and star formation efficiency in molecular clouds: solenoidal versus compressive motions in Orion B [PDF]
, 2017 Context. The nature of turbulence in molecular clouds is one of the key parameters that control star formation efficiency: compressive motions, as opposed to solenoidal motions, can trigger the collapse of cores, or mark the expansion of Hii regions ...
J. Orkisz +15 more
semanticscholar +1 more source
On the Spatial Distribution of 13CO Structures within 12CO Molecular Clouds
The Astrophysical Journal, 2023 We look into the 2851 ^12 CO molecular clouds harboring ^13 CO structures to reveal the distribution of the projected angular separations and radial velocity separations between their internal ^13 CO structures.
Lixia Yuan +10 more
doaj +1 more source
The approach to collapse of molecular clouds [PDF]
Monthly Notices of the Royal Astronomical Society, 2009 The dense molecular cloud cores that form stars, like other self-gravitating objects, undergo bulk oscillations. Just at the point of gravitational instability, their fundamental oscillation mode has zero frequency. We study, using perturbation theory, the evolution of a spherical cloud that possesses such a frozen mode.
Jeffrey J. Yen, Steven W. Stahler
openaire +3 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Supernova Driving. IV. The Star-formation Rate of Molecular Clouds [PDF]
, 2017 We compute the star-formation rate (SFR) in molecular clouds (MCs) that originate ab initio in a new, higher-resolution simulation of supernova-driven turbulence.
P. Padoan +3 more
semanticscholar +1 more source
Symposium - International Astronomical Union, 1992 Warm molecular gas is important in a large range of astronomical contexts. We discuss here determinations of the temperature and mass of warm material in protostellar disks and cores, photon dominated regions, and molecular material shocked by protostellar outflows. We then compare these results to heating and cooling models.
openaire +2 more sources
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Turbulence in Molecular Clouds [PDF]
, 1999 24 pages, 1 Latex file, 2 style files. To appear in ``Millimetric and Sub-Millimetric Astronomy. INAOE 1996 Summer School''
openaire +3 more sources
Molecular-Cloud Clusters and Chains [PDF]
Symposium - International Astronomical Union, 1985 We report some preliminary results from the Massachusetts - Stony Brook CO survey of the first galactic quadrant using the 14-meter millimeterwave telescope of the Five College Radio Astronomy Observatory. The survey contains approximately 50 000 observations spaced every 3 arcminutes in 1 and b between longitudes 0° and 90° and latitudes −1° and 1 ...
Sanders, D. B. +3 more
openaire +5 more sources