Results 91 to 100 of about 3,546,850 (294)

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang   +9 more
wiley   +1 more source

Herschel/HIFI observations of molecular lines toward G10.47+0.03

open access: yesFrontiers in Astronomy and Space Sciences
We present a spectral line analysis of the hot molecular core G10.47 + 0.03 (hereafter, G10). Our aim is to determine molecular abundances and excitation conditions across a wide spectral range inaccessible to ground-based observatories.
Indrajit Mondal   +12 more
doaj   +1 more source

The Nature of Shocks in Molecular Clouds [PDF]

open access: yesInternational Astronomical Union Colloquium, 1989
AbstractEvidence is presented to suggest that the shocked molecular hydrogen emission in the brightest part of the Orion outflow is produced in a J-shock and not a C-shock; that this is true throughout the entire flow; that it may be true in many outflow sources; and that this exacerbates problems with current explanations of the very wide velocity ...
openaire   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang   +18 more
wiley   +1 more source

Examining Turbulence in Galactic Molecular Clouds. I. A Statistical Analysis of Velocity Structures

open access: yesThe Astrophysical Journal
We present a systematic analysis of the velocity structure functions (VSFs) of 167 molecular clouds with angular sizes greater than ~176 arcmin ^2 in three sectors of the Galactic midplane.
Yuehui Ma   +16 more
doaj   +1 more source

Probing Molecular Clouds

open access: yes, 2007
. Knowledge of physical conditions in molecular clouds is a prerequisite for deriving the distribution of molecular material in the Milky Way and other galaxies, understanding star formation within these dense regions, the stellar initial mass function ...
Paul F. Goldsmith, Gamma Their
core  

Masses, luminosities and dynamics of galactic molecular clouds [PDF]

open access: yes, 1987
Star formation in galaxies takes place in molecular clouds and the Milky Way is the only galaxy in which it is possible to resolve and study the physical properties and star formation activity of individual clouds. The masses, luminosities, dynamics, and
Solomon, P. M.   +4 more
core  

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

open access: yesAdvanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao   +7 more
wiley   +1 more source

High altitude molecular clouds [PDF]

open access: yesThe Astrophysical Journal, 1994
A population of molecular clouds with a significantly greater scale height than that of Giant Molecular Clouds has been identified by examining maps of the latitude distribution of the $^{12}CO(1-0)$ emission in the first quadrant of the Galaxy. These clouds are found by identifying emission more than 2.6 times the scale-height away from the galactic ...
openaire   +2 more sources

High Altitude Molecular Clouds

open access: yes, 2007
A population of molecular clouds with a significantly greater scale height than that of Giant Molecular Clouds has been identified by examining maps of the latitude distribution of the 12 CO(1 \Gamma 0) emission in the first quadrant of the Galaxy ...
Sangeeta Malhotra
core  

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