Results 101 to 110 of about 224,084 (299)

Implementation Methods for Estimating Haplotypes with Grid Computing Technology [PDF]

open access: yes, 2010
Introduction: PHASE is a software for haplotype reconstruction and recombination rate estimation from population data and implements the methods for estimating haplotypes from population genotype data.
Sanjaya KC   +2 more
core   +2 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

DNA Computation Based Approach for Enhanced Computing Power [PDF]

open access: yes, 2011
DNA computing is a discipline that aims at harnessing individual molecules at the nano-scopic level for computational purposes. Computation with DNA molecules possesses an inherent interest for researchers in computers and biology.
Hameed, Kashif
core  

Membrane identity and GTPase cascades regulated by toggle and cut‐out switches

open access: yesMolecular Systems Biology, 2008
Key cellular functions and developmental processes rely on cascades of GTPases. GTPases of the Rab family provide a molecular ID code to the generation, maintenance and transport of intracellular compartments.
Perla Del Conte‐Zerial   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Molecular computers for molecular robots as hybrid systems

open access: yesTheoretical Computer Science, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Masami Hagiya   +3 more
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Generation of initial molecular dynamics configurations in arbitrary geometries and in parallel [PDF]

open access: yes, 2007
A computational pre-processing tool for generating initial configurations of molecules for molecular dynamics simulations in geometries described by a mesh of unstructured arbitrary polyhedra is described. The mesh is divided into separate zones and each
Borg, M.K.   +2 more
core   +1 more source

Programmable DNA‐Based Molecular Neural Network Biocomputing Circuits for Solving Partial Differential Equations

open access: yesAdvanced Science
Partial differential equations, essential for modeling dynamic systems, persistently confront computational complexity bottlenecks in high‐dimensional problems, yet DNA‐based parallel computing architectures, leveraging their discrete mathematics merits,
Yijun Xiao   +5 more
doaj   +1 more source

A DAG Scheduling Scheme on Heterogeneous Computing Systems Using Tuple-Based Chemical Reaction Optimization

open access: yesThe Scientific World Journal, 2014
A complex computing problem can be solved efficiently on a system with multiple computing nodes by dividing its implementation code into several parallel processing modules or tasks that can be formulated as directed acyclic graph (DAG) problems. The DAG
Yuyi Jiang, Zhiqing Shao, Yi Guo
doaj   +1 more source

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