Results 281 to 290 of about 770,458 (344)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Lubricin's Mucin Domain Has Strong Polyproline Type II Helical Character. [PDF]

Comput Struct Biotechnol J
Feng BN, Marks AJ, Kim FS, Naik M, Schmidt TA, Elsaid KA, Jay GD, Rubenstein BM.   +7 more
europepmc   +1 more source

Subphthalocyanine Platform for Single-Molecule Machines on Surface: Ligand-Directed Adsorption on Au(111). [PDF]

ACS Nano
Plate F, Park S, Cihan E, Khera N, Sun N, Das P, Guskova O, Ryndyk DA, Lissel F, Moresco F.   +9 more
europepmc   +1 more source

Molecular Origin of Correlated Bath Effects in Photoinduced Charge Transfer Dynamics in Polar Solvents. [PDF]

J Phys Chem Lett
Sun X, Liu Z.
europepmc   +1 more source

Revealing GRK5 Activation Features by Interpretable Machine Learning and Molecular Dynamics Simulation. [PDF]

Int J Mol Sci
Song Y, Kong M, Zhang F, Pu X.
europepmc   +1 more source

Molecular characterization of Mycoplasma synoviae in chickens in South Africa using single-stranded conformation polymorphism and high-resolution melting curve analysis of the vlhA gene

, 2013
Mashikoane Pinky Jane Raphela
openalex   +1 more source

Protein Conformations in the Gas Phase Probed by Mass Spectrometry and Molecular Dynamics Simulations

, 2019
Maryam Bakhtiari
openalex   +1 more source