Results 91 to 100 of about 589,238 (298)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Phonon scattering and heat transfer by "diffusive" modes in solid C6H6
Condensed Matter Physics, 2006 The isochoric thermal conductivity of solid C6H6 is described within a model in which the heat is transferred by phonons and above the phonon mobility edge by "diffusive" modes migrating randomly from site to site.
O.I.Pursky, V.A.Konstantinov
doaj +1 more source
Thermal Expansion in Dispersion-Bound Molecular Crystals
, 2018 We explore how anharmonicity, nuclear quantum effects (NQE), many-body dispersion interactions, and Pauli repulsion influence thermal properties of dispersion-bound molecular crystals.
Car, Roberto +3 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Application of retardation-modulation polarimetry in studies of nanocomposite materials
, 2019 We demonstrate an application of retardation-modulation polarimetry in studies of nanocomposite materials. Molecular ordering is explored on both nonchiral and chiral liquid crystals (LCs) in the bulk state and embedded into parallel-arrays of ...
Andrushchak, Anatoliy +4 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Science and Technology of Advanced Materials, 2017 In the development of innovative molecule-based materials, the identification of the structural features in supramolecular solids and the understanding of the correlation between structure and function are important factors.
Makoto Moriya
doaj +1 more source
Inorganic arrangement crystal beryllium, lithium, selenium and silicon
, 2015 The use of inorganic crystals technology has been widely date. Since quartz crystals for watches in the nineteenth century, and common way radio in the early twentieth century, to computer chips with new semiconductor materials. Chemical elements such as
Fedrigo, Desire Francine Gobato +2 more
core
Crystal engineering using functionalized adamantane
, 2010 We performed a first principles investigation on the structural, electronic, and optical properties of crystals made of chemically functionalized adamantane molecules.
Assali, L. V. C. +3 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source