Results 81 to 90 of about 589,238 (298)

Otto Stern (1888-1969): The founding father of experimental atomic physics

open access: yes, 2011
We review the work and life of Otto Stern who developed the molecular beam technique and with its aid laid the foundations of experimental atomic physics.
Friedrich, Bretislav   +3 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Tuning the Electrical Resistivity of Molecular Liquid Crystals for Electro-Optical Devices

open access: yesEngineering Proceedings
Modern applications of molecular liquid crystals span from high-resolution displays for augmented and virtual reality to miniature tunable lasers, reconfigurable microwave devices for space exploration and communication, and tunable electro-optical ...
Michael Gammon   +5 more
doaj   +1 more source

Theory of orientational ordering in colloidal molecular crystals

open access: yes, 2004
Freezing of charged colloids on square or triangular two-dimensional periodic substrates has been recently shown to realize a rich variety of orientational orders. We propose a theoretical framework to analyze the corresponding structures.
A. Chowdhury   +15 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

On the flexibility of the multipole model refinement. A DFT benchmark study of the tetrakis(μ-acetato)diaquadicopper model system

open access: yesIUCrJ
In this study, the flexibility of the multipole Hansen–Coppens (HC) model refinement is investigated on calculated structure factors from a DFT reference for the tetrakis(μ-acetato)diaquadicopper model system (CCDC reference 1811668).
Andrej Hlinčík   +5 more
doaj   +1 more source

An exceptional series of phase transitions in hydrophobic amino acids with linear side chains

open access: yesIUCrJ, 2016
The solid-state phase transitions and intermediate structures of S-2-aminobutanoic acid (l-2-aminobutyric acid), S-2-aminopentanoic acid (l-norvaline), S-2-aminohexanoic acid (l-norleucine) and l-methionine between 100 and 470 K, identified by ...
Carl Henrik Görbitz   +3 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Charge densities in actinide compounds: strategies for data reduction and model building

open access: yesIUCrJ, 2019
The data quality requirements for charge density studies on actinide compounds are extreme. Important steps in data collection and reduction required to obtain such data are summarized and evaluated.
Christopher G. Gianopoulos   +2 more
doaj   +1 more source

Hole Localization in Molecular Crystals From Hybrid Density Functional Theory

open access: yes, 2011
We use first-principles computational methods to examine hole trapping in organic molecular crystals. We present a computational scheme based on the tuning of the fraction of exact exchange in hybrid density functional theory to eliminate the many ...
Barbara, Paul F., Leung, Kevin, Sai, Na
core   +1 more source

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