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Newsletter Institute of Medical Molecular Biotechnology Issue 14 Disember 2021 / Institute of Medical Molecular Biotechnology [PDF]

, 2021
The Institute of Medical Molecular Biotechnology (IMMB) at Universiti Teknologi MARA (UiTM) launched its inaugural newsletter in November 2020. This publication serves as a platform to disseminate the institute's latest research activities, events, and ...
Universiti Teknologi MARA, Institute of Medical Molecular Biotechnology
core  

Vacuum-ultraviolet photoionization of a grandPAH molecule

Astronomy & Astrophysics
Context. So-called grandPAH molecules are proposed to be omnipresent in various interstellar regions as they are large enough to be photostable against strong interstellar radiation fields. They are also notoriously difficult to synthesize and sublimate.
Hrodmarsson Helgi Rafn, Jacovella Ugo, Pluta Serge, Yao Xuelin, Narita Akimitsu, Müllen Klaus, Schwell Martin, Linnartz Harold, Nahon Laurent, Giuliani Alexandre   +9 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Structural biology meets typography: using protein structures to inspire creative expression and connect diverse audiences

Frontiers in Bioinformatics
Proteins are complex molecular machines with specific structures that determine their function. Advances in structural bioinformatics and visualization have expanded access to molecular data, most notably through the Protein Data Bank (PDB).
Leonora Martínez-Núñez
doaj   +1 more source

Archives of Astronomical Spectral Observations and Atomic/Molecular Databases for their Analysis

Open Astronomy, 2015
We present a review of open-source data for stellar spectroscopy investigations. It includes lists of the main archives of medium-to-high resolution spectroscopic observations, with brief characteristics of the archive data (spectral range, resolving ...
Ryabchikova T., Pakhomov Yu.
doaj   +1 more source

Exploring character conflict in molecular data

Zootaxa, 2011
Mooi & Gill (2010) have made a number of criticisms of statistical approaches to the phylogenetic analysis of molecular data as it is currently practiced. There are many different uses for molecular phylogenies, and for most of them statistical methods are entirely appropriate, but for taxonomic purposes the way that these methods have been used is
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Growing Molecular Plant Sciences

, 2014
The VT Molecular Plant Sciences Magazine features the work of scientists and students in the department who use molecular approaches to unravel the mysteries of ...
Molecular Plant Sciences, Fralin Life Sciences Institute   +1 more
core  

Multimodal Non-Small Cell Lung Cancer Classification Using Convolutional Neural Networks

IEEE Access
Lung cancer is the leading cause of death worldwide. Early detection of lung cancer is a hard mission. New Small Cell Lung Cancer (NSCLC) is the most prevalent sub-type of lung cancer.
Marian Magdy Amin, Ahmed S. Ismail, Masoud E. Shaheen   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source