Results 181 to 190 of about 87,671 (216)

Similarity screening of molecular data sets

Journal of Computer-Aided Molecular Design, 1992
Three-dimensional (3D)-database searches are now being widely applied to determine potential new active molecules. Many structural data sets obtained as a result of these searches are still large in size. In this paper we apply molecular similarity calculations as a rapid method to screen two such data sets.
Andrew C. Good, Edward E. Hodgkin, W. Graham Richards   +2 more
openaire   +2 more sources

An XML repository for molecular sequence data

Proceedings IEEE International Symposium on Bio-Informatics and Biomedical Engineering, 2002
The emergence of the Extensible Markup Language (XML) as a new standard for data representation and exchange on the World Wide Web has created a new information revolution. Several proposals have been made to formulate molecular sequences in XML, however none of them mentioned the efficient storage and management of the resultant XML sequence data ...
Raymond K. Wong 0001, Franky Lam, Stephen C. Graham, William M. Shui   +3 more
openaire   +1 more source

Analysis of recombination in molecular sequence data

2008
Wir präsentieren Recco, eine neue und schnelle Methode zur Analyse von Rekombinationen in multiplen Alignments. Recco basiert auf einem dynamischen Programm, welches eine Sequenz im Alignment durch die anderen Sequenzen im Alignment rekonstruiert, wobei die Operatoren Mutation und Rekombination erlaubt sind.
openaire   +3 more sources

The applications of big data in molecular diagnostics

Expert Review of Molecular Diagnostics, 2019
Introduction: Big Data technologies instilled an informational perspective to our understanding of the world. However, fundamental issues such as the management and storage of data can create privacy concerns. Heterogeneous types of data pose challenges in reproducibility and standardization.
Yin Kwan Evelyn Wong, Ka Wai Lam, Ka Yi Ho, Chi Shing Allen Yu, Chi Shing William Cho, Hin Fung Tsang, Man Kee Maggie Chu, Po Wah Lawrence Ng, Chi Shing William Tai, Lawrence Wing Chi Chan, Elaine Yue Ling Wong, Sze Chuen Cesar Wong   +11 more
openaire   +3 more sources

Molecular data on cystic fibrosis in Bulgaria

Human Genetics, 1990
A group of 42 cystic fibrosis (CF) patients and 80 heterozygote carriers was analysed for determining the prevalent CF haplotypes and the frequency of delta F508. The "high-risk" haplotype B (XV2c-KM19/1 2) was found in 66% of CF chromosomes. The prevalent normal haplotypes were A (1 1) and B (2 1). The deletion was detected in 54 CF chromosomes (56%),
L, Kalaydjieva, J, Antov, J, Bronzova, V, Vladimirova, J, Horst   +4 more
openaire   +2 more sources

Molecular immunology databases and data repositories

Journal of Immunological Methods, 2000
Over recent years databases have become an extremely important resource for biomedical research. Immunology research is increasingly dependent on access to extensive biological databases to extract existing information, plan experiments, and analyse experimental results.
Brusic, Vladimir, Zeleznikow, John, Petrovsky, Nikolai   +2 more
openaire   +5 more sources

Atomic and Molecular Data

1994
In recent years the interaction between astrophysics and atomic physics has entered a new stage. On one hand, increasingly powerful, high resolution astronomical spectrometers and other observational instruments, especially those for recent space and astronomy missions, have created vastly increased demands for more detailed and more accurate data on ...
openaire   +1 more source

The Impact of Molecular Data in Fungal Systematics

2005
Molecular data has been used in fungal systematics since the 1970s, and its rate of incorporation has increased significantly in recent years. In phylogeny molecular data has already been used to clarify major evolutionary lines, and has aided in the delineation of higher taxonomic groups including the kingdom Fungi, and the main phyla within it ...
Bridge, P.D., Spooner, B.M., Roberts, P.J.   +2 more
openaire   +2 more sources

Atomic and Molecular Data

1985
As the pool of fundamental data available to astronomers continues to increase, the question of how best to promote the necessary cross-discipline interaction becomes increasingly important. Commission 14 has traditionally played an important role in this activity, by publishing triennial reports in the IAU Proceedings, as well as by responding to more
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Cancer: smoother journeys for molecular data

Nature Methods, 2015
Data integration and tool interoperability can ease analyses of cancer 'omics data and yield surprises.
openaire   +2 more sources