Results 11 to 20 of about 1,017,559 (266)

The inverted pattern of circulating miR-221-3p and miR-222-3p associated with isolated low HDL-C phenotype

Lipids in Health and Disease, 2018
Background We investigated the baseline characterization of cardiovascular disease (CVD)-derived circulating miR-221-3p/222-3p in isolated low HDL-C phenotype (ILHP) to enhance our understanding on their molecular pathological pattern prior to disease ...
Yuntao Zhou, Mengdi Liu, Jinrong Li, Bing Wu, Wei Tian, Lu Shi, Jing Zhang, Zening Sun   +7 more
doaj   +1 more source

Small intestinal bacterial overgrowth as a cause of protracted wound healing and vitamin D deficiency in a spinal cord injured patient with a sacral pressure sore: a case report

BMC Gastroenterology, 2020
Background Pressure sores are sometimes refractory to treatment, often due to malnutrition. Small intestinal bacterial overgrowth (SIBO) obstructs absorption in the digestive tract and causes malnutrition.
Yoshitaka Kubota, Hidekazu Nagano, Kentaro Ishii, Takashi Kono, Satomi Kono, Shinsuke Akita, Nobuyuki Mitsukawa, Tomoaki Tanaka   +7 more
doaj   +1 more source

Treatment patterns and outcomes in older women with early breast cancer: a population-based cohort study in China

BMC Cancer, 2021
Background Despite the proportion of elderly breast cancer patients has been consistently increasing, the optimal treatment modalities for this population have not been well explored. We summarized the treatment outcomes of these patients in our hospital.
Xu Liu, Dan Zheng, Yanqi Wu, Chuanxu Luo, Yu Fan, Xiaorong Zhong, Hong Zheng   +6 more
doaj   +1 more source

Molecular Diagnosis of Mycobacteria [PDF]

Clinical Chemistry, 2001
AbstractTuberculosis is one of the leading infectious diseases in the world and is responsible for more than 2 million deaths and 8 million new cases annually. Because of the slow growth rate of the causative agent Mycobacterium tuberculosis, isolation, identification, and drug susceptibility testing of this organism and other clinically important ...
H, Soini, J M, Musser
openaire   +2 more sources

Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors

Communications Biology, 2022
The genetic alterations, protein expressions, and clinical characteristics of growth hormone-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors are integrated to detect molecules associated with acromegaly characteristics.
Azusa Yamato, Hidekazu Nagano, Yue Gao, Tatsuma Matsuda, Naoko Hashimoto, Akitoshi Nakayama, Kazuyuki Yamagata, Masataka Yokoyama, Yingbo Gong, Xiaoyan Shi, Siti Nurul Zhahara, Takashi Kono, Yuki Taki, Naoto Furuki, Motoi Nishimura, Kentaro Horiguchi, Yasuo Iwadate, Masaki Fukuyo, Bahityar Rahmutulla, Atsushi Kaneda, Yoshinori Hasegawa, Yusuke Kawashima, Osamu Ohara, Tetsuo Ishikawa, Eiryo Kawakami, Yasuhiro Nakamura, Naoko Inoshita, Shozo Yamada, Noriaki Fukuhara, Hiroshi Nishioka, Tomoaki Tanaka   +30 more
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Pyroptosis-Related Subtypes Predict the Response of Clear Cell Renal Cell Carcinoma to Targeted Therapy

Frontiers in Bioscience-Landmark, 2023
Background: Pyroptosis plays a crucial role in anti-tumor immunity and in formation of the immune microenvironment. However, whether pyroptosis is involved in the progression of clear cell renal cell carcinoma (ccRCC) is still unclear.
Jinpeng Ma, Zhijian Kang, Guang Yang, Xinyue Wang, Minggui Si, Yuting Wang, Guangbin Li, Shiyu Bai, Fanshu Zeng, Min Li, Ziqi Wang, Lu Wang, Wanhai Xu   +12 more
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Molecular diagnosis of deafness

AUDIOLOGY JAPAN, 2011
Despite advances in discovery of deafness genes, clinical application still entails difficulties because of the genetic heterogeneity of deafness. In order to establish strategy for clinical application, we reviewed the genes responsible for hearing loss patients in Japan (Usami S et al; Acta Otolaryngol 128: 446-454, 2008), and discussed diagnostic ...
openaire   +4 more sources

Molecular Diagnosis of Medical Viruses [PDF]

Current Issues in Molecular Biology, 2007
The diagnosis of infectious diseases has been revolutionized by the development of molecular techniques, foremost with the applications of the polymerase chain reaction (PCR). The achievable high sensitivity and ease with which the method can be used to detect any known genetic sequence have led to its wide application in the life sciences.
Ratcliff, R. M., Chang, G., TuckWeng, K., Sloots, T. P.   +3 more
openaire   +6 more sources

PDGFB targeting biodegradable FePt alloy assembly for MRI guided starvation-enhancing chemodynamic therapy of cancer

Journal of Nanobiotechnology, 2022
The application of chemodynamic therapy (CDT) for cancer is a serious challenge owing to the low efficiency of the Fenton catalyst and insufficient H2O2 expression in cells.
Caiyun Zhang, Zhiguo Leng, Yinfeng Wang, Lang Ran, Xia Qin, Huan Xin, Xiaotong Xu, Guilong Zhang, Zhaowei Xu   +8 more
doaj   +1 more source

Acetylation of Checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer

Cell Death Discovery, 2022
Checkpoint suppressor 1 (CHES1), a transcriptional regulator, had been dysregulated in many types of malignancies including breast cancer, and its expression level is strongly associated with progression and prognosis of patients. However, the underlying
Zhaowei Xu, Shuyan Liu, Chun Feng, Fuyi Xu, Demin Kong, Jia Mi, Chunhua Yang, Guilong Zhang, Pengfei Wei, Buyan-Ochir Orgil, Jonas Bergquist, Geng Tian   +11 more
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