Results 21 to 30 of about 1,119,993 (215)

Tuberculosis in antiretroviral treatment services in resource-limited settings: addressing the challenges of screening and diagnosis. [PDF]

, 2011
The high burden of tuberculosis (TB) among patients accessing antiretroviral treatment (ART) services in resource-limited settings is a major cause of morbidity and mortality and is associated with nosocomial transmission risk.
Lawn, Stephen D, Robin Wood, Wood, Robin, Stephen D. Lawn   +3 more
core   +1 more source

Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors

Communications Biology, 2022
The genetic alterations, protein expressions, and clinical characteristics of growth hormone-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors are integrated to detect molecules associated with acromegaly characteristics.
Azusa Yamato, Hidekazu Nagano, Yue Gao, Tatsuma Matsuda, Naoko Hashimoto, Akitoshi Nakayama, Kazuyuki Yamagata, Masataka Yokoyama, Yingbo Gong, Xiaoyan Shi, Siti Nurul Zhahara, Takashi Kono, Yuki Taki, Naoto Furuki, Motoi Nishimura, Kentaro Horiguchi, Yasuo Iwadate, Masaki Fukuyo, Bahityar Rahmutulla, Atsushi Kaneda, Yoshinori Hasegawa, Yusuke Kawashima, Osamu Ohara, Tetsuo Ishikawa, Eiryo Kawakami, Yasuhiro Nakamura, Naoko Inoshita, Shozo Yamada, Noriaki Fukuhara, Hiroshi Nishioka, Tomoaki Tanaka   +30 more
doaj   +1 more source

PDGFB targeting biodegradable FePt alloy assembly for MRI guided starvation-enhancing chemodynamic therapy of cancer

Journal of Nanobiotechnology, 2022
The application of chemodynamic therapy (CDT) for cancer is a serious challenge owing to the low efficiency of the Fenton catalyst and insufficient H2O2 expression in cells.
Caiyun Zhang, Zhiguo Leng, Yinfeng Wang, Lang Ran, Xia Qin, Huan Xin, Xiaotong Xu, Guilong Zhang, Zhaowei Xu   +8 more
doaj   +1 more source

Pyroptosis-Related Subtypes Predict the Response of Clear Cell Renal Cell Carcinoma to Targeted Therapy

Frontiers in Bioscience-Landmark, 2023
Background: Pyroptosis plays a crucial role in anti-tumor immunity and in formation of the immune microenvironment. However, whether pyroptosis is involved in the progression of clear cell renal cell carcinoma (ccRCC) is still unclear.
Jinpeng Ma, Zhijian Kang, Guang Yang, Xinyue Wang, Minggui Si, Yuting Wang, Guangbin Li, Shiyu Bai, Fanshu Zeng, Min Li, Ziqi Wang, Lu Wang, Wanhai Xu   +12 more
doaj   +1 more source

Molecular diagnosis of deafness

AUDIOLOGY JAPAN, 2011
Despite advances in discovery of deafness genes, clinical application still entails difficulties because of the genetic heterogeneity of deafness. In order to establish strategy for clinical application, we reviewed the genes responsible for hearing loss patients in Japan (Usami S et al; Acta Otolaryngol 128: 446-454, 2008), and discussed diagnostic ...
openaire   +4 more sources

Molecular Diagnosis of Medical Viruses [PDF]

Current Issues in Molecular Biology, 2007
The diagnosis of infectious diseases has been revolutionized by the development of molecular techniques, foremost with the applications of the polymerase chain reaction (PCR). The achievable high sensitivity and ease with which the method can be used to detect any known genetic sequence have led to its wide application in the life sciences.
Ratcliff, R. M., Chang, G., TuckWeng, K., Sloots, T. P.   +3 more
openaire   +6 more sources

Acetylation of Checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer

Cell Death Discovery, 2022
Checkpoint suppressor 1 (CHES1), a transcriptional regulator, had been dysregulated in many types of malignancies including breast cancer, and its expression level is strongly associated with progression and prognosis of patients. However, the underlying
Zhaowei Xu, Shuyan Liu, Chun Feng, Fuyi Xu, Demin Kong, Jia Mi, Chunhua Yang, Guilong Zhang, Pengfei Wei, Buyan-Ochir Orgil, Jonas Bergquist, Geng Tian   +11 more
doaj   +1 more source

Pollen Allergens for Molecular Diagnosis [PDF]

Current Allergy and Asthma Reports, 2016
Pollen allergens are one of the main causes of type I allergies affecting up to 30% of the population in industrialized countries. Climatic changes affect the duration and intensity of pollen seasons and may together with pollution contribute to increased incidences of respiratory allergy and asthma.
Pablos, Isabel, Wildner, Sabrina, Asam, Claudia, Wallner, Michael, Gadermaier, Gabriele   +4 more
openaire   +3 more sources

Molecular diagnosis of parasites

Experientia, 1991
New developments in molecular biology have generated exciting possibilities for improved diagnosis of parasitic diseases. Through gene cloning and expression and peptide synthesis, defined parasite antigens can be produced in vitro for use in serodiagnosis, while nuclear hybridization techniques offer a vastly improved approach to identification of ...
openaire   +3 more sources

Molecular Diagnosis of Polymicrobial Sepsis [PDF]

Journal of Clinical Microbiology, 2009
The recognition of sepsis is a crucial aspect in the management of critically ill patients. Recent guidelines strongly recommend the initiation of broad-spectrum antibiotic therapy within 1 hour after the recognition of a case of sepsis ([1][1]).
MANCINI , NICASIO, Carletti S, Ghidoli N, Cichero P, Ossi CM, Ieri R, Poli E, BURIONI , ROBERTO, CLEMENTI , MASSIMO   +8 more
openaire   +2 more sources