Results 31 to 40 of about 4,757,335 (242)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Single molecule tracking of the molecular mobility in thinning liquid films on thermally grown SiO2 [PDF]

open access: yes, 2009
Diffusion coefficients obtained from weighted mean square displacements along probe molecule trajectories within ultrathin liquid TEHOS films show a correlation with film thickness.
Heidernätsch, Mario   +5 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Through Diffusion Measurements of Molecules to a Numerical Model for Protein Crystallization in Viscous Polyethylene Glycol Solution

open access: yesCrystals, 2022
Protein crystallography has become a popular method for biochemists, but obtaining high-quality protein crystals for precise structural analysis and larger ones for neutron analysis requires further technical progress.
Hiroaki Tanaka   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Magnetic resonance spectral characterization of diffusion with chemical shift resolution [PDF]

open access: yes, 2009
We present a modulated gradient spin-echo method (MGSE), which uses a train of sinusoidally shaped gradient pulses separated by 180-degree RF pulses.
Topgaard, Daniel   +2 more
core   +1 more source

Numerical Modelling of Gas Mixing in Salt Caverns During Cyclic Hydrogen Storage

open access: yesEnergies
This study presents the development of a robust numerical model for simulating underground hydrogen storage (UHS) in salt caverns, with a particular focus on the interactions between original gas-methane (CH4) and injected gas represented by hydrogen (H2)
Krzysztof Miłek, Wiesław Szott
doaj   +1 more source

Effect of diffusion on interfacial properties of polyurethane-modified asphalt–aggregate using molecular dynamic simulation

open access: yesReviews on Advanced Materials Science, 2022
In order to understand the diffusion behavior of polyurethane (PU) in asphalt and the adhesion between modified asphalt and aggregate, the diffusion system of PU-modified asphalt was studied by molecular dynamics simulation software.
Zhao Song   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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