Results 41 to 50 of about 4,757,335 (242)

NMR methods for the fast recording of diffusion [PDF]

, 2007
The time taken to complete an NMR diffusion experiment is typically ~10 minutes. For systems that rapidly evolve conventional pulsed field gradient spin-echo (PGSE) experiments cannot be used to obtain reliable estimates of molecular mobility.
Pages, Guilhem, Kuchel, Philip W.
core   +1 more source

Justification of technological solutions for methods of prediction and control of deposits in trunk pipelines

Технічна інженерія
To substantiate technologically and economically viable methods for predicting deposit formation kinetics and implementing integrated control strategies in trunk pipelines, with emphasis on coupling predictive modeling, preventive inhibition, thermal ...
V.O. Rastsvietaiev, V.V. Yavorska, D.O. Vasylchenko, D.O. Yashyn, M.Ye. Koroviaka   +4 more
doaj   +1 more source

High-Throughput Sequencing, a VersatileWeapon to Support Genome-Based Diagnosis in Infectious Diseases: Applications to Clinical Bacteriology

Pathogens, 2014
The recent progresses of high-throughput sequencing (HTS) technologies enable easy and cost-reduced access to whole genome sequencing (WGS) or re-sequencing.
Ségolène Caboche, Christophe Audebert, David Hot   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

High efficiency diffusion molecular retention tumor targeting. [PDF]

PLoS ONE, 2013
Here we introduce diffusion molecular retention (DMR) tumor targeting, a technique that employs PEG-fluorochrome shielded probes that, after a peritumoral (PT) injection, undergo slow vascular uptake and extensive interstitial diffusion, with tumor ...
Yanyan Guo, Hushan Yuan, Hoonsung Cho, Darshini Kuruppu, Kimmo Jokivarsi, Aayush Agarwal, Khalid Shah, Lee Josephson   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Significance of Low‐Velocity Zones on Solute Retention in Rough Fractures

Water Resources Research
Natural fractures are characterized by high internal heterogeneity. This internal variability is the cause of flow channeling, which in turn leads to contaminant transport taking place primarily along the high‐velocity channels. Mass exchange between the
Jordi Sanglas, Paolo Trinchero, Scott L. Painter, Vladimir Cvetkovic, Antti Poteri, Jan‐Olof Selroos, Liangchao Zou   +6 more
doaj   +1 more source

Simulation and Sensitivity Analysis of CO₂ Migration and Pressure Propagation Considering Molecular Diffusion and Geochemical Reactions in Shale Oil Reservoirs

Energies
Unconventional shale oil reservoirs, characterized by ultra-low porosity and permeability, severely constrain oil recovery. CO2-enhanced oil recovery (CO2-EOR) following hydraulic fracturing is an effective approach that combines incremental oil recovery
Ruihong Qiao, Bing Yang, Hai Huang, Qianqian Ren, Zijie Cheng, Huanyu Feng   +5 more
doaj   +1 more source