Homology modeling and molecular docking simulation of some novel imidazo[1,2-a]pyridine-3-carboxamide (IPA) series as inhibitors of Mycobacterium tuberculosis. [PDF]
J Genet Eng Biotechnol, 2021 Abdullahi M +3 more
europepmc +1 more source
Molecular Docking Simulation to Predict Inhibitors Against Zinc Transporters
Zinc is one of the essential elements required by our body for normal functioning. This zinc concentration inside the cell is maintained by a particular type of protein called zinc transporter (ZnT). These transporters actively transport zinc ions outside the cells and playplay an important role in diabetes.
Irene Batta, Gaurav Sharma
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Biotechnology and Bioengineering, EarlyView.ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan +4 more
wiley +1 more source
Combatting biofilm formation of Klebsiella pneumoniae and Bacillus subtilis clinical strains from the oral cavity using biogenic Se-NPs: molecular docking simulation and cytotoxic effects on HepG2 cancer cells. [PDF]
BMC MicrobiolYousef A +5 more
europepmc +1 more source
Computational details of molecular structure, spectroscopic properties, topological studies and SARS-Cov-2 enzyme molecular docking simulation of substituted triazolo pyrimidine thione heterocycles. [PDF]
Spectrochim Acta A Mol Biomol Spectrosc, 2021 El Sayed DS, Abdelrehim EM.
europepmc +1 more source
Transfer Learning Approaches in Bioprocess Engineering: Opportunities and Challenges
Biotechnology and Bioengineering, EarlyView.ABSTRACT Transfer learning (TL) has recently emerged as a promising approach to overcoming one of the key limitations of bioprocess engineering: data scarcity. By leveraging knowledge from one bioprocess to another, TL allows existing models and data sets to be reused efficiently, accelerating process development, improving prediction accuracy, and ...
Daniel Barón Díaz +3 more
wiley +1 more source
Astragalin improves cognitive disorder in Alzheimer's disease: Based on network pharmacology and molecular docking simulation. [PDF]
CNS Neurosci TherDu R +7 more
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Biotechnology and Bioengineering, EarlyView.ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal +2 more
wiley +1 more source
Identification of Molecular Mechanisms of Ameloblastoma and Drug Repositioning by Integration of Bioinformatics Analysis and Molecular Docking Simulation. [PDF]
Bioinform Biol InsightsChujan S +3 more
europepmc +1 more source
BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source