Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Molecular dynamics of the matrisome across sea anemone life history. [PDF]
Bergheim BG +7 more
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Comparing cryo-EM methods and molecular dynamics simulation to investigate heterogeneity in ligand-bound TRPV1. [PDF]
Astore MA +4 more
europepmc +1 more source
Exploring the temperature stability of CRISPR-Cas12b using molecular dynamics simulations.
Jia Y +4 more
europepmc +1 more source
Identification of bioactive phytoconstituents as promising ABL2 inhibitors using virtual screening and molecular dynamics simulation. [PDF]
Elayyan AEM +4 more
europepmc +1 more source
Molecular dynamics simulation of Sunset Yellow dye removal from water using hydrochar adsorbent. [PDF]
Ho TH +4 more
europepmc +1 more source
Investigation into Laser-Vibration-Assisted Cutting of Single-Crystal Silicon by Molecular Dynamics Simulation. [PDF]
Chu J +8 more
europepmc +1 more source

