Results 41 to 50 of about 2,029,549 (348)

Metagenomic analysis of human, animal, and environmental samples identifies potential emerging pathogens, profiles antibiotic resistance genes, and reveals horizontal gene transfer dynamics

open access: yesScientific Reports
Antimicrobial resistance (AMR) poses a significant threat to global health. The indiscriminate use of antibiotics has accelerated the emergence and spread of drug-resistant bacteria, compromising our ability to treat infectious diseases.
Rajindra Napit   +12 more
doaj   +1 more source

Control of randomly scattered surface plasmon polaritons for multiple-input and multiple-output plasmonic switching devices

open access: yesNature Communications, 2017
Losses of bandwidth are inevitable when interfacing between optical and electronic components. Here the authors present a switching device consisting of a two-dimensional disordered array of nanoholes that can potentially transfer information about 40 ...
Wonjun Choi   +6 more
doaj   +1 more source

Marcus inverted region of charge transfer from low-dimensional semiconductor materials

open access: yesNature Communications, 2021
Marcus inverted region for charge transfer from low-dimensional semiconductor materials has been long sought after. Here, the authors reveal this region by directly measuring charge transfer from single-charge states rather than excitonic states.
Junhui Wang   +5 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Time-reversible Born-Oppenheimer molecular dynamics [PDF]

open access: yes, 2006
We present a time-reversible Born-Oppenheimer molecular dynamics scheme, based on self-consistent Hartree-Fock or density functional theory, where both the nuclear and the electronic degrees of freedom are propagated in time.
Anders M. N. Niklasson   +4 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Ultrafast fluxional exchange dynamics in electrolyte solvation sheath of lithium ion battery

open access: yesNature Communications, 2017
The lithium solvation structure in the electrolyte solution for lithium-ion batteries has not been fully understood. Here, the authors show ultrafast fluxional exchange of carbonate solvent molecules in and out of lithium-ion solvation sheath utilizing ...
Kyung-Koo Lee   +6 more
doaj   +1 more source

Feasibility study of a novel general purpose CZT-based digital SPECT camera: initial clinical results

open access: yesEJNMMI Physics, 2018
Background The performance of a prototype novel digital single-photon emission computed tomography (SPECT) camera with multiple pixelated CZT detectors and high sensitivity collimators (Digital SPECT; Valiance X12 prototype, Molecular Dynamics) was ...
Elinor Goshen   +5 more
doaj   +1 more source

Laser scanning reflection-matrix microscopy for aberration-free imaging through intact mouse skull

open access: yesNature Communications, 2020
Microscopic imaging of the brain usually requires thinning of the skull, as it causes complex aberration. Here, the authors introduce a label-free imaging modality termed laser scanning reflection-matrix microscopy, which allows for correcting these ...
Seokchan Yoon   +4 more
doaj   +1 more source

Effective Sampling in the Configurational Space by the Multicanonical-Multioverlap Algorithm

open access: yes, 2006
We propose a new generalized-ensemble algorithm, which we refer to as the multicanonical-multioverlap algorithm. By utilizing a non-Boltzmann weight factor, this method realizes a random walk in the multi-dimensional, energy-overlap space and explores ...
B. A. Berg   +5 more
core   +1 more source

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