Results 71 to 80 of about 6,867,350 (304)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Molecular dynamics as an approach to study prion protein misfolding and the effect of pathogenic mutations [PDF]

, 2011
Computer simulation of protein dynamics offers unique high-resolution information that complements experiment. Using experimentally derived structures of the natively folded prion protein (PrP), physically realistic dynamics and conformational changes ...
Valerie Daggett, Daggett, Valerie, van der Kamp, Marc W, Marc W. van der Kamp   +3 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Label-free neuroimaging in vivo using synchronous angular scanning microscopy with single-scattering accumulation algorithm

Nature Communications, 2019
A major challenge of in vivo imaging is imaging deeper, including in turbid tissue. The authors report an adaptive optics based microscope that uses coherent single scattering signal to reduce sample-induced aberrations and enable fast deep-tissue ...
Moonseok Kim, Yonghyeon Jo, Jin Hee Hong, Suhyun Kim, Seokchan Yoon, Kyung-Deok Song, Sungsam Kang, Byunghak Lee, Guang Hoon Kim, Hae-Chul Park, Wonshik Choi   +10 more
doaj   +1 more source

On the dynamics of molecular conformation [PDF]

Proceedings of the National Academy of Sciences, 2006
Understanding the mechanism of fast transitions between conformed states of large biomolecules is central to reconciling the dichotomy between the relatively high speed of metabolic processes and slow (random-walk based) estimates on the speed of biomolecular processes.
openaire   +2 more sources

Molecular dynamics simulations from putative transition states of alpha-spectrin SH3 domain

, 2007
A series of molecular dynamics simulations in explicit solvent were started from nine structural models of the transition state of the SH3 domain of alpha-spectrin, which were generated by Lindorff Larsen et al.
Mark, AE, Vendruscolo, Michele, Mark, Alan E., Vendruscolo, M, Alan E. Mark, Periole, X, Periole, Xavier, Xavier Periole, Michele Vendruscolo   +8 more
core   +1 more source

Acceleration of Coarse Grain Molecular Dynamics on GPU Architectures [PDF]

, 2013
Coarse grain (CG) molecular models have been proposed to simulate complex sys- tems with lower computational overheads and longer timescales with respect to atom- istic level models.
Acquaviva*, Andrea, FICARRA, ELISA, ACQUAVIVA, ANDREA, Enrico Macii, Andrea Acquaviva, Elisa Ficarra, SHKURTI, ARDITA, Ardita Shkurti, Macii, Enrico, Ficarra*, Elisa, Mario Orsi, Orsi, Mario   +11 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Machine-learning enhanced simulations predict graphene is microscopically hydrophobic and not wetting transparent

Nature Communications
The interaction between graphene and water is fundamental to applications ranging from filtration to nano-electronics, yet the intrinsic wettability of graphene remains a subject of longstanding debate.
Dianwei Hou, Yevhen Horbatenko, Stefan Ringe, Minhaeng Cho   +3 more
doaj   +1 more source

Fermionic molecular dynamics [PDF]

Nuclear Physics A, 1989
Abstract A new type of molecular dynamics is proposed to solve approximately the many-body problem of interacting identical fermions with spin 1 2 . The interacting system is represented by an antisymmetrized many-body wave function consisting of single-particle states which are localized in phase space.
openaire   +1 more source