Results 81 to 90 of about 6,867,350 (304)

Determining the structure of interfacial peptide films: comparing neutron reflectometry and molecular dynamics simulations

, 2014
The peptides AM1 and Lac21E self-organize into switchable films at an air-water interface. In an earlier study, it was proposed that both AM1 and Lac21E formed monolayers of α-helical peptides based on consistency with neutron reflectivity data.
Xue, Ying, Mark, Alan E., Poger, D., Middelberg, A., He, Lizhong, Poger, David, He, L., Middelberg, Anton P. J., Ying Xue, David Poger, Alan E. Mark, Mark, A., Lizhong He, Anton P. J. Middelberg, Xue, Y.   +14 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modelling abrasive machining techniques using molecular dynamics [PDF]

, 2008
The development of ultra–precision processes which can achieve nanometre surface finishes and tolerances is now a critical requirement for many applications in medical, electronics and energy industry.
Oluwajobi, Akinjide O., Chen, Xun
core   +4 more sources

A Molecular Dynamics Study of the Formation, Stability, and Oligomerization State of Two Designed Coiled Coils: Possibilities and Limitations [PDF]

, 2005
The formation, relative stability, and possible stoichiometries of two (self-)complementary peptide sequences (B and E) designed to form either a parallel homodimeric (B+B) or an antiparallel heterodimeric (B+E) coiled coil have been investigated ...
Villa, Alessandra, Vagt, Toni, Koksch, Beate, Mark, Alan E., Koksch, B., Pinero, A., Piñeiro, Ángel, Mark, A.E., Vagt, T.   +8 more
core   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Infrared spectroscopic study of hydrogen bonding topologies in the smallest ice cube

Nature Communications, 2020
Spectroscopic studies of water clusters provide insight into the hydrogen bond structure of water and ice. The authors measure infrared spectra of neutral water octamers using a threshold photoionization technique based on a tunable vacuum-UV free ...
Gang Li, Yang-Yang Zhang, Qinming Li, Chong Wang, Yong Yu, Bingbing Zhang, Han-Shi Hu, Weiqing Zhang, Dongxu Dai, Guorong Wu, Dong H. Zhang, Jun Li, Xueming Yang, Ling Jiang   +13 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Two-dimensional infrared spectroscopic study of cytochrome c peroxidase activity in deep eutectic solvent

Structural Dynamics, 2019
Deep eutectic solvents (DESs) prepared by mixing hydrogen-bond donor and acceptor molecules have been found to be of use in several applications. Recently, it was shown that DESs can enhance the peroxidation activity of cytochrome c.
Koji Osawa, Dorota Kossowska, Kwanghee Park, Kyungwon Kwak, Minhaeng Cho   +4 more
doaj   +1 more source

Deep tissue space-gated microscopy via acousto-optic interaction

Nature Communications, 2020
In ideal diffraction-limited optical microscopy imaging depth is limited by the multiply scattered wave. Here, the authors present a space gating method, based on an acoustic focus in the object plane and reconstruction using only the acousto-optically ...
Mooseok Jang, Hakseok Ko, Jin Hee Hong, Won Kyu Lee, Jae-Seung Lee, Wonshik Choi   +5 more
doaj   +1 more source

Pseudoatom molecular dynamics

Physical Review E, 2015
A new approach to simulating warm and hot dense matter that combines density functional theory based calculations of the electronic structure to classical molecular dynamics simulations with pair interaction potentials is presented. The new method, which we call pseudoatom molecular dynamics (PAMD), can be applied to single or multi-component plasmas ...
Starrett, C. E., Daligault, J., Saumon, D.   +2 more
openaire   +4 more sources