Results 51 to 60 of about 17,737,336 (290)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The problem of obtaining crystaline phases during cooling binary nanoparticles Au-Co and Ti-V

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2023
The processes of structure formation in Co-Au and Ti-V metal nanoparticles as well as factors affecting the crystallization process are considered. The objects of the study were Co-Au and Ti-V binary nanoparticles containing N = 400, 800, 1520 and 5000 ...
K.G. Savina, R.E. Grigoryev, A.D. Veselov, S.S. Bogdanov, P.M. Ershov, S.A. Veresov, D.R. Zorin, V.S. Myasnichenko, N.Yu. Sdobnyakov   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

To the problem of tight binding potential parameters approbation: influence of the ratio between pair and many-body interaction on the process of the structure formation in binary Pd-Pt nanoparticles

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов
The reliability of the atomistic simulation is determined in terms of the correctness of the problem statement, including the choice of the interatomic interaction potential and its parameterization. In this paper, a detailed testing of the tight-binding
N.Yu. Sdobnyakov, A.Yu. Kolosov, D.N. Sokolov, K.G. Savina, N.I. Nepsha, Ya.P. Savel’ev, G.D. Lomonosov   +6 more
doaj   +1 more source

INFLUENCE OF THE SIZE EFFECT ON THE REGULARITIES OF THE STRUCTURE FORMATION IN BIMETALLIC Au-Co NANOPARTICLES

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2021
This work studied bimetallic Au-Co nanoparticles of three stoichiometric compositions of various sizes by the molecular dynamics method using the tight-binding potential.
N.Yu. Sdobnyakov, S.S. Bogdanov, A.D. Veselov, K.G. Savina, N.I. Nepsha, A.Yu. Kolosov, V.S. Myasnichenko   +6 more
doaj   +1 more source

Molecular dynamics studies of ultrafast laser-induced phase and structural change in crystalline silicon [PDF]

, 2012
In this work, thermodynamic phenomena in crystalline silicon irradiated by an ultrafast laser pulse were studied using the method of molecular dynamics simulations. The Stillinger-Weber potential was used to model the crystalline silicon. The temperature
Yang, Chengjuan, Xu, Xianfan, Wang, Yaguo   +2 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Applications of the molecular dynamics flexible fitting method [PDF]

Journal of Structural Biology, 2011
In recent years, cryo-electron microscopy (cryo-EM) has established itself as a key method in structural biology, permitting the structural characterization of large biomolecular complexes in various functional states. The data obtained through single-particle cryo-EM has recently seen a leap in resolution thanks to landmark advances in experimental ...
Trabuco, L., SchreineR, E., Gumbart, J., Hsin, J., Villa, E., Schulten, K.   +5 more
openaire   +3 more sources

A concurrent multiscale method based on the meshfree method and molecular dynamics analysis [PDF]

, 2006
This paper presents a concurrent simulation technique for analysing the deformation of systems that need the integration of material properties from nanoscopic to macroscopic dimensional scales.
Zhang, L.C., Gu, YuanTong
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source