Results 71 to 80 of about 17,737,336 (290)

COMPUTER MODELS OF DEALLOYING IN BINARY METAL NANOPARTICLES

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2019
Two alternative molecular dynamics models (programs) involving the Gupta (tight-binding) potential have been used to reproduce the dealloying phenomenon in the Au – Ag nanoalloy. Program I successively removes Ag atoms from the particle surface layer (we
V.S. Myasnichenko, V.M. Samsonov, N.Yu. Sdobnyakov, A.G. Bembel, S.A. Vasilyev, A.Yu. Kolosov, K.G. Savina, P.M. Ershov, D.N. Sokolov   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

MD-based study on the deformation process of engineered Ni–Al core–shell nanowires: Toward an understanding underlying deformation mechanisms

Curved and Layered Structures, 2023
Nowadays, core/shell structures due to very high thermal and electrical conductivity are taken into account in the manufacture of many industrial sensors and catalysis.
Mohammed Bassam A., Batbooti Raed S.
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Structural transformations in quaternary nanoalloys Cu-Au-Pt-Pd of different morphology under successive thermally induced cycles

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов
A molecular dynamics study of the structure formation processes in four-component Cu-Au-Pt-Pd nanoparticles (with a total number of 4000 atoms) was carried out during two successive cycles of thermally induced action.
S.V. Serov, N.I. Nepsha, A.Yu.. Kolosov, D.N. Sokolov, K.G. Savina, S.A. Veresov, N.Yu.. Sdobnyakov   +6 more
doaj   +1 more source

Study on the temperature dependence of the bulk modulus of polyisoprene by molecular dynamics simulations [PDF]

, 2008
The temperature dependence of the bulk modulus of polyisoprene has been studied using molecular dynamics simulations. Virtual polyisoprenes have been submitted to volume contractions above and below the glass transition. Bulk modulus has been observed to
GILORMINI, Pierre, DIANI, Julie, FAYOLLE, Bruno   +2 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Molecule diffusion behaviours of waterproof sealants into silicone rubber insulation for submarine cable joint based on molecular dynamics simulations

High Voltage, 2021
The repair joints of high‐voltage cables play a significant role in the urgent cable maintenance, by recovering cable conductor, insulation, shielding layer and waterproof layer especially for submarine cables.
Zhenpeng Zhang, Heyu Wang, Zhonglei Li, Jiankang Zhao, Shaohua Wang, Wenlin Pan, Wenjie Li, Te Li, Boxue Du   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source