Results 221 to 230 of about 4,041,148 (293)

Distinct Molecular Pathways Supporting Sjögren Disease Clusters and Disease Progression

Arthritis &Rheumatology, EarlyView.
Objective Sjögren disease (SjD) is a heterogeneous autoimmune disease. We aimed to investigate blood transcriptomic signatures and disease progression among three recently defined clusters of patients with SjD: (1) B cell active disease with low symptom burden (BALS), (2) high systemic activity (HSA), and (3) low systemic activity with high symptom ...
Sacha E. Silva‐Saffar, Yann Nguyen, Raphaèle Seror, Jacques‐Eric Gottenberg, Anna Niarakis, Xavier Mariette, Gaetane Nocturne   +6 more
wiley   +1 more source

Molecular epidemiology and geographic distribution of <i>Theileria</i> spp. in Kazakhstan: a countrywide cattle survey and a southern sheep survey. [PDF]

Front Vet Sci
Mukanov K, Ostrovskii A, Kamalova D, Ryskeldina A, Kassen A, Berdikulov M, Abdrakhmanov S, Shevtsov A, Bauer C.   +8 more
europepmc   +1 more source

Comparative Transcriptional Profiling of Key Macrophage and Fibroblast Subpopulations in Rheumatoid Arthritis–Associated Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib, Ogechukwu Ezenwa, Joshua Sciurba, Eleanor B. Valenzi, John Sembrat, Brittany Cody, Jishnu Das, Robert Lafyatis, Dana P. Ascherman   +8 more
wiley   +1 more source

Role of casual contact in drug-resistant tuberculosis transmission: a molecular epidemiology study. [PDF]

Am J Respir Crit Care Med
Gandhi NR, Naidoo K, Lutchminarain K, Omar SV, Yoshii H, Willis F, Boodhram R, Gwala T, Campbell A, Coe MM, Evans AN, Tang L, Chitwood MH, Hlathi SR, Mbatha PN, Joseph L, Van Der Meulen H, Mlisana K, Jenness SM, Lurie MN, Kreiswirth BN, Warren JL, Nelson KN, Auld SC, Brust JCM, Cohen T, Mathema B, Shah NS.   +27 more
europepmc   +1 more source

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

Arthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen, Sanjaykumar Boddul, Zhaojun Li, Zsolt Kasza, Marlene Schülein, Bruno Raposo, Karine Chemin, Per‐Johan Jakobsson, Alexander Espinosa, Lars Klareskog, Fredrik Wermeling   +10 more
wiley   +1 more source

Research note: Molecular epidemiology of Marek's disease virus in China during 2022 and 2023. [PDF]

Poult Sci
Yan C, Wei X, Zhong Q, Jin W, Yang Y, Wang Z, Peng D.   +6 more
europepmc   +1 more source

Genetic and Population Analyses Implicate Thyroid‐Related Regulation of RNF144B in Chondrocalcinosis

Arthritis &Rheumatology, EarlyView.
Objective Chondrocalcinosis, characterized by calcium crystal deposition within articular cartilage, affects 5% to 15% of the general population and has recently been identified as an osteoarthritis risk factor. However, its biologic pathways remain unclear.
Yahong Wu, Yanning Xu, Paul C. Okoro, Sirine Saafi, Jard de Vries, Xiaoyi Qi, Edwin H. G. Oei, Sita Bierma‐Zeinstra, Trudy Voortman, David Felson, Joyce B. J. van Meurs, Layal Chaker, J. Mark Wilkinson, Michelle S. Yau, Jessica Bertrand, Cindy G. Boer   +15 more
wiley   +1 more source

Molecular Epidemiology of Helminths at the Wildlife-Livestock Interface in Kazakhstan: Evidence from Sheep and Saiga. [PDF]

Pathogens
Abekeshev N, Ussenov Z, Abdrakhmanov R, Aitpayeva Z, Svotina M, Valiyeva Z, Zhumabayev A, Darmenova A, Abirova I, Ryskaliyeva Z, Aitkaliyev A, Kaliyeva A, Berkaliyeva A, Bissalyyeva R, Zhanabayev A, Abulgazimova G.   +15 more
europepmc   +1 more source

Plasma Proteome Reflects Tissue Damage and Clinical Manifestations in Patients With Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo, Josefin Kenrick, Angeles S. Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E. Lundberg, Begum Horuluoglu   +23 more
wiley   +1 more source

Molecular Epidemiology of Skin-Dwelling Filariae and Risk Factors for Mansonella streptocerca Infection, Gabon. [PDF]

Emerg Infect Dis
Sicard CM, Fischer M, Wizemann C, Bartling M, Martin L, Rodi M, Inoue J, Sinopoli SV, Mehmel E, Kreidenweiss A, Matsiegui PB, Ramharter M, Agnandji ST, Held J.   +13 more
europepmc   +1 more source