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Molecular epidemiology: The impact of molecular biology in epidemiology research
Progress in molecular biology and genetics is changing the practice of medicine and public health through the development of molecular diagnostics and targeted interventions for susceptible individuals. The ethical, legal and social issues that are becoming apparent as these important discoveries are introduced into practice will have an enormous ...
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ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Epidemiology of colorectal cancer. [PDF]
Colorectal cancer is currently the third deadliest cancer in the United States and will claim an estimated 49,190 U.S. lives in 2016. The purpose of this review is to summarize our current understanding of this disease, based on nationally published ...
Nan, Hongmei, Marley, Andrew R.
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ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
The future of molecular epidemiology [PDF]
Subdomains of epidemiological activity classified according to techniques have been shorter-lived than those classified by the type of disease or exposure. Most of us feel comfortable with broad categories defined by disease group (such as ‘cancer epidemiology’) or by exposure (‘nutritional epidemiology’).
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The integration of molecular tools into veterinary and spatial epidemiology
At the interface of molecular biology and epidemiology, the emerging discipline of molecular epidemiology offers unique opportunities to advance the study of diseases through the investigation of infectious agents at the molecular level.
Ruth N. Zadoks +18 more
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ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Molecular epidemiology of the leprosy
Application of molecular biological techniques to the epidemiological study of leprosy is described. Studies of detecting Mycobacterium leprae DNA in samples of the nasal mucus are discussed in terms of the epidemiology and the significance of high prevalence.
Matsuoka, Masanori, Zhang, Liangfen
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The molecular epidemiology of parasite infections: Tools and applications [PDF]
Molecular epidemiology, broadly defined, is the application of molecular genetic techniques to the dynamics of disease in a population. In this review, we briefly describe molecular and analytical tools available for molecular epidemiological studies and
Thompson, R.C.A., Lymbery, A.J.
core
Bioinformatics challenges in molecular epidemiology of cancers [PDF]
Molecular epidemiology is the integration of molecular biologic techniques into epidemiologic study. With the advances in understanding of carcinogenesis and the human genome, there has been an evolution in the field of cancer epidemiology.
Se Hoon Park, Hong-Hee Won
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