Results 61 to 70 of about 321,049 (302)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Molecular epidemiology of C. pneumoniae infections

Microbiologia Medica, 2010
Introduction. Chlamydophila pneumoniae (C. pneumoniae) is one of the most common respiratory pathogen, with an incidence of infection varying from 6% to 20%. The present study aimed to assess the incidence of C.
Alisa Shurdhi, Federica Delucca, Francesca Savegnago, Maria Di Paolo, Manuela Donati   +4 more
doaj   +1 more source

Leishmaniases in the Mediterranean in the era of molecular epidemiology.

, 2008
Molecular tools are used increasingly for descriptive epidemiological studies in different Mediterranean foci of visceral and cutaneous leishmaniases.
Gramiccia, Marina, Mauricio, I., Marina Gramiccia, Carmen Cañavate, Isabel Mauricio, Jean-Claude Dujardin, Cañavate, Carmen, Marleen Boelaert, Dujardin, Jean-Claude, Dujardin, J. C., Mauricio, Isabel, Gramiccia, M., Boelaert, M., Schönian, G., Boelaert, Marleen, Gabriele Schönian, Cañavate, C., Schönian, Gabriele   +17 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Molecular Epidemiology of Cryptosporidiosis in China

Frontiers in Microbiology, 2017
Molecular epidemiology of cryptosporidiosis is an active research area in China. The use of genotyping and subtyping tools in prevalence studies has led to the identification of unique characteristics of Cryptosporidium infections in humans and animals ...
Yaoyu Feng, Lihua Xiao
doaj   +1 more source

Molecular epidemiology of seal parvovirus, 1988-2014. [PDF]

PLoS ONE, 2014
A novel parvovirus was discovered recently in the brain of a harbor seal (Phoca vitulina) with chronic meningo-encephalitis. Phylogenetic analysis of this virus indicated that it belongs to the genus Erythroparvovirus, to which also human parvovirus B19 ...
Rogier Bodewes, Rebriarina Hapsari, Ana Rubio García, Guillermo J Sánchez Contreras, Marco W G van de Bildt, Miranda de Graaf, Thijs Kuiken, Albert D M E Osterhaus   +7 more
doaj   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Molecular Genetics and Epidemiology of Vitiligo: A Minireview [PDF]

International Journal of Epidemiologic Research, 2018
Background and aims: Vitiligo is an acquired, idiopathic, and common depigmentation disorder of the skin that affects people of all ages and both sexes equally worldwide. Although etiology of the disease is unknown, there are theories such as environment
Shahrzad Aghaeii, Masoud Amiri, Maryam Aghaei, Mohammad Ali Nilforoushzadeh   +3 more
doaj   +1 more source

Molecular Pathological Epidemiology Gives Clues to Paradoxical Findings

, 2019
A number of epidemiologic studies have described what appear to be paradoxical associations, where an incongruous relationship is observed between a certain well-established risk factor for disease incidence and favorable clinical outcome among patients ...
Wang, Molin, Nishihara, Reiko, Shibuya, Kenji, Ogino, Shuji, VanderWeele, Tyler, Giovannucci, Edward, Field, Alison, Lochhead, Paul, Mittleman, Murray   +8 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source