Results 121 to 130 of about 5,499,417 (372)

Major results and research challenges in cotton molecular genetics at Cirad (France) [PDF]

open access: yes, 2008
CIRAD (Montpellier, France) develops research activities centered on tropical and sub-tropical agricultural systems. Among others crops, cotton is the fucus of a series of research programs in different disciplines from economics to breeding. Major areas
Claverie, Michel   +4 more
core  

Molecular genetics of AML [PDF]

open access: yesBest Practice & Research Clinical Haematology, 2012
In the past decade, a series of technological advances have revolutionized our ability to interrogate cancer genomes, culminating in whole-genome sequencing, which provides genome-wide coverage at a single base-pair resolution. To date, the tumor genome has been sequenced in nearly 40 cases of acute myeloid leukemia (AML).
openaire   +3 more sources

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]

open access: yes, 2008
Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
A Bultreys   +38 more
core   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Molecular genetics for familial hypercholesterolemia [PDF]

open access: yesReviews in Cardiovascular Medicine, 2022
Nicola Marziliano   +4 more
doaj   +1 more source

Molecular genetics related to non-Hodgkin lymphoma

open access: yesOpen Life Sciences, 2016
Non-Hodgkin lymphoma (NHL) is a serious disease, with a high proportion of mortality. Molecular genetic abnormalities are very common in NHL, but specific characterization in accordance to molecular genetics for lymphoma subtypes is not yet completed ...
Guo Ming, Mao Xianglin, Ding Xiaoqing
doaj   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Stealing the riches: using the human genome project for livestock research [PDF]

open access: yes, 2002
The document attached has been archived with permission from the Australian Association of Cattle Veterinarians.The human genome project has brought a new era not only to medical genetics, but also to livestock molecular genetics.
Bottema, C.
core  

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