Results 231 to 240 of about 5,499,417 (372)

Molecular genetics of early-onset Alzheimer's disease revisited

open access: yesAlzheimer's & Dementia, 2016
Rita Cacace, K. Sleegers, C. Broeckhoven
semanticscholar   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

State of the Art on Inherited Retinal Dystrophies: Management and Molecular Genetics. [PDF]

open access: yesJ Clin Med
Nebbioso M   +6 more
europepmc   +1 more source

Molecular genetics of Alport syndrome: the clinical consequences [PDF]

open access: bronze, 1993
Bertrand Knebelmann   +3 more
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Molecular Genetics of Renal Cell Carcinoma: A Narrative Review Focused on Clinical Relevance. [PDF]

open access: yesCurr Oncol
Millan B   +6 more
europepmc   +1 more source

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