Results 241 to 250 of about 4,885,439 (330)

Molecular genetics of testicular germ cell tumors.

, 2012
Yuri Sheikine, Elizabeth M. Genega, Jonathan Melamed, Peng Lee, Victor E. Reuter, Huihui Ye   +5 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Integrating in situ strategies and molecular genetics for the conservation of the endangered Azorean endemic plant Lotus azoricus. [PDF]

Sci Rep
Rego RMC, Silva L, Olangua-Corral M, Roxo G, Resendes R, Herrezuelo AG, Bettencourt J, Freitas C, Pereira D, Moura M.   +9 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Editorial: Recent advances in the molecular genetics of glioma. [PDF]

Front Genet
Chung C, Buczkowicz P.
europepmc   +1 more source

Molecular genetics of oogenesis in Drosophila melanogaster

, 2004
Silvia Gigliotti, V. Cavaliere, Giuseppe Gargiulo, Franco Graziani, C. Malva   +4 more
openalex   +1 more source

Genetics and molecular mechanism of trimethylamine N-oxide demethylase of Methylocella silvestris BL2 [PDF]

, 2016
Yijun Zhu
openalex  

Genetics and Molecular Biology of Hydrogen Metabolism in Sulfate-Reducing Bacteria

, 2014
Judy D. Wall
openalex   +2 more sources

Molecular Genetics [PDF]

, 1991
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source