Results 271 to 280 of about 5,499,417 (372)

Molecular genetics of hvDOchondroDlasia

Clinical Endocrinology, 1991
openaire   +3 more sources

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Integrating in situ strategies and molecular genetics for the conservation of the endangered Azorean endemic plant Lotus azoricus. [PDF]

Sci Rep
Rego RMC, Silva L, Olangua-Corral M, Roxo G, Resendes R, Herrezuelo AG, Bettencourt J, Freitas C, Pereira D, Moura M.   +9 more
europepmc   +1 more source

The premature retina: A model for the in vivo study of molecular genetics?

, 1992
John T. Flynn
openalex   +1 more source

DnaSP version 3: an integrated program for molecular population genetics and molecular evolution analysis

Bioinform., 1999
J. Rozas, R. Rozas
semanticscholar   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Sex-based differences in lung cancer susceptibility and molecular genetics in the 2020s. [PDF]

Heliyon
Mosleh B, Sarova P, Zehetmayer S, Oberndorfer F, Widder J, Prosch H, Idzko M, Aigner C, Hoda MA, Gompelmann D.   +9 more
europepmc   +1 more source

Primer on molecular genetics

, 1992

openalex   +1 more source

Molecular genetics of attention deficit hyperactivity disorder.

Psychiatric Clinics of North America, 2010
S. Faraone, E. Mick
semanticscholar   +1 more source