Results 71 to 80 of about 5,499,417 (372)
Unifying the essential concepts of biological networks: biological insights and philosophical foundations [PDF]
, 2020 Over the last decades, network-based approaches have become highly popular in diverse fields of biology, including neuroscience, ecology, molecular biology and genetics.
Hilgetag, Claus +2 more
core +2 more sources
Genetic and molecular epidemiology [PDF]
Journal of Epidemiology & Community Health, 2007 Genetic and molecular epidemiology covers a vast area of research. Given the rapid changes in this field, discussing a research agenda is a precarious and ambitious task. A representative set of high-priority concepts will be presented here, each of which alone could be the topic of a long series of essays.
openaire +3 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Evolving Molecular Genetics of Glioblastoma
Chinese Medical Journal, 2016 Objective: To summary the recent advances in molecular research of glioblastoma (GBM) and current trends in personalized therapy of this disease. Data Sources: Data cited in this review were obtained mainly from PubMed in English up to 2015, with ...
Qiu-Ju Li, Jin-Quan Cai, Cheng-Yin Liu
doaj +1 more source
Genetic and functional analysis reveals TENM4 contributes to schizophrenia
iScience, 2021 Summary: TENM4, encoding a member of the teneurin protein family, is a risk gene shared by many types of mental diseases and is implicated in neuronal plasticity and signaling.
Xin Yi +12 more
doaj +1 more source
The genetics and genomics of Trypanosoma cruzi [PDF]
, 2007 Trypanosoma cruzi is a kinetoplastid parasite that causes Chagas disease. Trypanosomes are unusual organisms in many aspects of its genetics and molecular and cellular biology and considered a paradigm of the exception of the rule in the eukaryotic ...
Vazquez, Martin Pablo
core
A Portuguese patient homozygous for the -25G>A mutation of the HAMP promoter shows evidence of steady-state transcription but fails to up-regulate hepcidin levels by iron. [PDF]
, 2005 Blood. 2005 Oct 15;106(8):2922-3. A Portuguese patient homozygous for the -25G>A mutation of the HAMP promoter shows evidence of steady-state transcription but fails to up-regulate hepcidin levels by iron.
Almeida, S. +8 more
core +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Molecular Genetics of Gastric Adenocarcinoma
Proceedings of Singapore Healthcare, 2010 Gastric carcinoma is the second leading cause of cancer deaths in the world. Its aetiology is closely linked to the bacterial pathogen Helicobacter pylori which is believed to induce a state of chronic inflammation that predisposes to a cascade of ...
Alvin Kim Hock Eng MMed (Surgery), FRCSEd +1 more
doaj +1 more source
Molecular Genetics of Turcot’s Syndrome
Pediatric Neurology Briefs, 1995 Genetic abnormalities in 13 of 14 families with concurrent primary brain tumors and multiple colorectal adenomas (Turcot’s syndrome) are reported from the Johns Hopkins University School of Medicine and other centers.
J Gordon Millichap
doaj +1 more source