Results 61 to 70 of about 1,769,037 (315)

Identification of the Kna/Knb polymorphism and a method for Knops genotyping

, 2004
DNA mutations resulting in the McCoy and Swain-Langley polymorphisms have been identified on complement receptor 1 (CR1)-a ligand for rosetting of Plasmodium falciparum-infected RBCs. The molecular identification of the Kna/Knb polymorphism was sought to
Moulds, J M, Thomas, B J, Rowe, J A; id_orcid, Doumbo, O, Lyke, K E, Birmingham, D J, Plowe, C V, Diallo, D A   +7 more
core   +1 more source

Molecular Detection and Identification of Plant-Associated Lactiplantibacillus plantarum

, 2023
Lactiplantibacillus plantarum is a lactic acid bacterium often isolated from a wide variety of niches. Its ubiquity can be explained by a large, flexible genome that helps it adapt to different habitats. The consequence of this is great strain diversity,
Magdalena Skotniczny, Paweł Satora
core   +1 more source

Pathological changes in the spleen of mice subjected to different time courses of restraint stress

Scientific Reports
The objective of this study was to investigate spleen pathology and immune cell subset alterations in mice exposed to acute and chronic restraint stress over various timeframes.
Lei Lei, Yingmin Li, Meili Li, Hongjian Xin, Xiaofei Tian, Yifan Zhang, Weibo Shi, Bin Cong   +7 more
doaj   +1 more source

Forensic age estimation from human blood using age-related microRNAs and circular RNAs markers

Frontiers in Genetics, 2022
Aging is a complicated process characterized by progressive and extensive changes in physiological homeostasis at the organismal, tissue, and cellular levels.
Junyan Wang, Haixia Zhang, Chunyan Wang, Lihong Fu, Qian Wang, Shujin Li, Bin Cong   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Microbiota-associated metabolite pantothenic acid enhances skeletal muscle contusion repair via epigenetic regulation of macrophage M2 polarization

Journal of Translational Medicine
Background The quality of skeletal muscle contusion repair hinges on the timely resolution of inflammation and the initiation of regeneration, processes in which M2 macrophage polarization plays a critical role.
Lin Wu, Yifan Zhang, Guowei Zhang, Xiaowei Feng, Weihao Zhu, Huihuang Yang, Xin Ji, Meifang Yin, Shujin Li, Yingmin Li, Weibo Shi, Bin Cong   +11 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Molecular neuropathology of gliomas

, 2009
Gliomas are the most common primary human brain tumors. They comprise a heterogeneous group of benign and malignant neoplasms that are histologically classified according to the World Health Organization (WHO) classification of tumors of the nervous ...
Markus Riemenschneider, Riemenschneider, Markus J., Reifenberger, Guido, Guido Reifenberger   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source