Results 41 to 50 of about 3,022,035 (311)

Using molecular tools to differentiate closely related blackfly species of the genus Simulium [PDF]

, 2009
Biodiversity data are the foundation for conservation and managemet and taxonomy provides the reference system, skills and tools used to identify organisms.
Day, J. C.
core  

Forensic age estimation from human blood using age-related microRNAs and circular RNAs markers

Frontiers in Genetics, 2022
Aging is a complicated process characterized by progressive and extensive changes in physiological homeostasis at the organismal, tissue, and cellular levels.
Junyan Wang, Haixia Zhang, Chunyan Wang, Lihong Fu, Qian Wang, Shujin Li, Bin Cong   +6 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Pathological changes in the spleen of mice subjected to different time courses of restraint stress

Scientific Reports
The objective of this study was to investigate spleen pathology and immune cell subset alterations in mice exposed to acute and chronic restraint stress over various timeframes.
Lei Lei, Yingmin Li, Meili Li, Hongjian Xin, Xiaofei Tian, Yifan Zhang, Weibo Shi, Bin Cong   +7 more
doaj   +1 more source

Norepinephrine-Activated p38 MAPK Pathway Mediates Stress-Induced Cytotoxic Edema of Basolateral Amygdala Astrocytes

Brain Sciences
The amygdala is a core region in the limbic system that is highly sensitive to stress. Astrocytes are key players in stress disorders such as anxiety and depression. However, the effects of stress on the morphology and function of amygdala astrocytes and
Zhaoling Sun, Xiaojing Zhang, Yiming Dong, Yichang Liu, Chuan Wang, Yingmin Li, Chunling Ma, Guangming Xu, Songjun Wang, Chenteng Yang, Guozhong Zhang, Bin Cong   +11 more
doaj   +1 more source

Similarity-based data mining in files of two-dimensional chemical structures using fingerprint measures of molecular resemblance [PDF]

, 2011
This paper reviews the use of measures of intermolecular similarity for processing databases of chemical structures, which play an important role in the discovery of new drugs by the pharmaceutical industry.
Willett, P.
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Microbiota-associated metabolite pantothenic acid enhances skeletal muscle contusion repair via epigenetic regulation of macrophage M2 polarization

Journal of Translational Medicine
Background The quality of skeletal muscle contusion repair hinges on the timely resolution of inflammation and the initiation of regeneration, processes in which M2 macrophage polarization plays a critical role.
Lin Wu, Yifan Zhang, Guowei Zhang, Xiaowei Feng, Weihao Zhu, Huihuang Yang, Xin Ji, Meifang Yin, Shujin Li, Yingmin Li, Weibo Shi, Bin Cong   +11 more
doaj   +1 more source

Morphological re-description and molecular identification of Tabanidae (Diptera) in East Africa [PDF]

, 2018
Biting flies of the family Tabanidae are important vectors of human and animal diseases across continents. However, records of Africa tabanids are fragmentary and mostly cursory.
Ciosi, Marc, Gitau, Joseph, Masiga, Daniel, Mugasa, Claire M., Ndungu, Nelly, Villinger, Jandouwe   +5 more
core   +2 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source