Results 31 to 40 of about 12,274,852 (362)

Enhanced Extraction of Blood and Tissue Time-Activity Curves in Cardiac Mouse FDG PET Imaging by Means of Constrained Nonnegative Matrix Factorization

open access: yesInternational Journal of Biomedical Imaging, 2023
We propose an enhanced method to accurately retrieve time-activity curves (TACs) of blood and tissue from dynamic 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) positron emission tomography (PET) cardiac images of mice. The method is noninvasive and consists
Otman Sarrhini   +4 more
doaj   +1 more source

Noninvasive molecular imaging of neuroinflammation [PDF]

open access: yes, 2011
Inflammation is a highly dynamic and complex adaptive process to preserve and restore tissue homeostasis. Originally viewed as an immune-privileged organ, the central nervous system (CNS) is now recognized to have a constant interplay with the innate and
Jacobs, A.H. (Andreas)   +13 more
core   +1 more source

Nanobody: a promising toolkit for molecular imaging and disease therapy

open access: yesEJNMMI Research, 2021
Nanobodies are the recombinant variable domains of heavy-chain-only antibodies, with many unique properties such as small size, excellent solubility, superior stability, quick clearance from blood, and deep tissue penetration.
Guangfa Bao   +3 more
semanticscholar   +1 more source

Cardiovascular molecular imaging [PDF]

open access: yes, 2013
Although there have been significant improvements in the treatment of cardiovascular diseases they still remain the main cause of morbidity and mortality globally. Currently available diagnostic approaches may not be adequate to detect pathologic changes
Khanicheh, Elham
core   +1 more source

Molecular breast imaging [PDF]

open access: yesExpert Review of Anticancer Therapy, 2009
Molecular breast imaging (MBI) is a new nuclear medicine technique that utilizes small semiconductor-based gamma-cameras in a mammographic configuration to provide high-resolution functional images of the breast. Current studies with MBI have used Tc-99m sestamibi, which is an approved agent for breast imaging.
Michael, O'Connor   +2 more
openaire   +2 more sources

Evaluation of the novel TSPO radiotracer [18F] VUIIS1008 in a preclinical model of cerebral ischemia in rats

open access: yesEJNMMI Research, 2017
Background In vivo positron-emission tomography (PET) imaging of transporter protein (TSPO) expression is an attractive and indispensable tool for the diagnosis and therapy evaluation of neuroinflammation after cerebral ischemia.
Krishna R. Pulagam   +7 more
doaj   +1 more source

High-Throughput Molecular Imaging via Deep-Learning-Enabled Raman Spectroscopy [PDF]

open access: yesAnalytical Chemistry, 2020
Raman spectroscopy enables nondestructive, label-free imaging with unprecedented molecular contrast, but is limited by slow data acquisition, largely preventing high-throughput imaging applications.
C. Horgan   +6 more
semanticscholar   +1 more source

Molecular imaging and immunotherapy [PDF]

open access: yesThe International Journal of Biological Markers, 2020
The utility of positron emission tomography (PET) for the evaluation of response to immunotherapy has been considered a hot topic, particularly in the last 2 to 3 years. Different experiences have been collected in clinical practice, with 18F-Fluorodeoxyglucose (FDG) PET/computed tomography (CT), particularly in patients affected by lymphoma, malignant
openaire   +4 more sources

Pathophysiology and Molecular Imaging of Diabetic Foot Infections

open access: yesInternational Journal of Molecular Sciences, 2021
Diabetic foot infection is the leading cause of non-traumatic lower limb amputations worldwide. In addition, diabetes mellitus and sequela of the disease are increasing in prevalence. In 2017, 9.4% of Americans were diagnosed with diabetes mellitus (DM).
Katie L Rubitschung   +11 more
semanticscholar   +1 more source

Multi-scale optoacoustic molecular imaging of brain diseases

open access: yesEuropean Journal of Nuclear Medicine and Molecular Imaging, 2021
The ability to non-invasively visualize endogenous chromophores and exogenous probes and sensors across the entire rodent brain with the high spatial and temporal resolution has empowered optoacoustic imaging modalities with unprecedented capacities for ...
D. Razansky, J. Klohs, R. Ni
semanticscholar   +1 more source

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