Results 61 to 70 of about 1,886,243 (328)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

High-speed centrifugation induces aggregation of extracellular vesicles [PDF]

Journal of Extracellular Vesicles, 2015
Plasma and other body fluids contain cell-derived extracellular vesicles (EVs), which participate in physiopathological processes and have potential biomedical applications.
Romain Linares, Sisareuth Tan, Céline Gounou, Nicolas Arraud, Alain R. Brisson   +4 more
doaj   +1 more source

A shallow though extensive H2 2.12 micron imaging survey of Taurus-Auriga-Perseus: I. NGC1333, L1455, L1448 and B1

, 2008
We discuss wide-field near-IR imaging of the NGC1333, L1448, L1455 and B1 star forming regions in Perseus. The observations have been extracted from a much larger narrow-band imaging survey of the Taurus-Auriga-Perseus complex.
A. Adamson, Allen, Arce, Aspin, Bachiller, Bally, Bally, Bate, Bontemps, C. J. Davis, Casali, Chrysostomou, Dame, Davis, Davis, Davis, de Zeeuw, Dobashi, Dye, Eislöffel, Eislöffel, Evans, Evans, Fazio, Gutermuth, Gutermuth, Harvey, Harvey, Hatchell, Hatchell, Hatchell, Heathcote, Hewett, Hirano, Hodapp, Hodapp, Jennings, Jørgensen, Jørgensen, Kirk, Kirk, Knee, Kumar, Lada, Ladd, Lawrence, Lee, Lopez, Lucas, Luhman, Luhman, M. D. Smith, P. Lucas, P. Scholz, Ridge, Rieke, Rodriguez, Sargent, Smith, Smith, Takami, Terquem, Tobin, Velusamy, Walawender, Walawender, Walawender, Ward-Thompson, Whitney, Černis   +69 more
core   +1 more source

Interventional Molecular Imaging [PDF]

Radiology, 2010
Recent common interest in molecular imaging among both diagnostic and interventional radiologists has led to the establishment of a concept that could be called interventional molecular imaging. This concept, by combining interventional radiology with molecular imaging, is aiming to fully apply the advantages of both imaging fields.
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Molecular Imaging of Microglial Activation in Amyotrophic Lateral Sclerosis [PDF]

, 2012
There is growing evidence of activated microglia and inflammatory processes in the cerebral cortex in amyotrophic lateral sclerosis (ALS). Activated microglia is characterized by increased expression of the 18 kDa translocator protein (TSPO) in the brain
Arlicot, Nicolas, Baulieu, Jean-Louis, Corcia, Philippe, Cottier, Jean-Philippe, Guilloteau, Denis, Hommet, Caroline, Kassiou, Michael, Nicolas, Guillaume, Praline, Julien, Prunier, Caroline, Ribeiro, Maria-Joao, Roussel, Catherine, Tauber, Clovis, Venel, Yann, Vercouillie, Johnny   +14 more
core   +2 more sources

Molecular imaging and immunotherapy [PDF]

The International Journal of Biological Markers, 2020
The utility of positron emission tomography (PET) for the evaluation of response to immunotherapy has been considered a hot topic, particularly in the last 2 to 3 years. Different experiences have been collected in clinical practice, with 18F-Fluorodeoxyglucose (FDG) PET/computed tomography (CT), particularly in patients affected by lymphoma ...
openaire   +4 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Comparison of integrin α v β 3 expression with 68Ga-NODAGA-RGD PET/CT and glucose metabolism with 18F-FDG PET/CT in esophageal or gastroesophageal junction cancers

European Journal of Hybrid Imaging, 2023
Background The primary aims of this study were to compare in patients with esophageal or esophagogastric junction cancers the potential of 68Ga-NODAGA-RGD PET/CT with that of 18F-FDG PET/CT regarding tumoral uptake and distribution, as well as ...
Matthieu Dietz, Vincent Dunet, Styliani Mantziari, Anastasia Pomoni, Ricardo Dias Correia, Nathalie Testart Dardel, Sarah Boughdad, Marie Nicod Lalonde, Giorgio Treglia, Markus Schafer, Niklaus Schaefer, John O. Prior   +11 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source