Results 61 to 70 of about 12,274,852 (362)

Molecular and functional imaging in cancer-targeted therapy: current applications and future directions

Signal Transduction and Targeted Therapy, 2023
Targeted anticancer drugs block cancer cell growth by interfering with specific signaling pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing cells as in cytotoxic chemotherapy.
Jing-Wen Bai, Si-qi Qiu, Guo‐Jun Zhang
semanticscholar   +1 more source

Development and Evaluation of 18F-IRS for Molecular Imaging Mutant EGF Receptors in NSCLC

Scientific Reports, 2017
To prepare and evaluate a new radiotracer 18F-IRS for molecular imaging mutant EGF Receptors in vitro and vivo. Uptake and efflux of 18F-IRS were performed with four NSCLC cell lines including HCC827, H1975, H358 and H520.
Yan Song, Zunyu Xiao, Kai Wang, Xiance Wang, Chongqing Zhang, Fang Fang, Xilin Sun, Baozhong Shen   +7 more
doaj   +1 more source

The Future of Nuclear Medicine, Molecular Imaging, and Theranostics.

Journal of Nuclear Medicine, 2020
### Wolfgang A. Weber and Johannes Czernin Scientific discoveries published in The Journal of Nuclear Medicine over the past 60 years have shaped the practice of medicine and form the foundation for the future of nuclear medicine, molecular imaging, and
W. Weber, J. Czernin, C. Anderson, R. Badawi, H. Barthel, F. Bengel, L. Bodei, I. Buvat, M. DiCarli, M. Graham, Jan Grimm, Jan Grimm, K. Herrmann, L. Kostakoglu, Jason S. Lewis, Jason S. Lewis, D. Mankoff, Todd E. Peterson, H. Schelbert, H. Schöder, B. Siegel, H. Strauss   +21 more
semanticscholar   +1 more source

Multi-tracer and multiparametric PET imaging to detect the IDH mutation in glioma: a preclinical translational in vitro, in vivo, and ex vivo study

Cancer Imaging, 2022
Background This translational study explores multi-tracer PET imaging for the non-invasive detection of the IDH1 mutation which is a positive prognostic factor in glioma.
Alexandra Clément, Timothee Zaragori, Romain Filosa, Olga Ovdiichuk, Marine Beaumont, Charlotte Collet, Emilie Roeder, Baptiste Martin, Fatiha Maskali, Muriel Barberi-Heyob, Celso Pouget, Matthieu Doyen, Antoine Verger   +12 more
doaj   +1 more source

Multivalent Probes in Molecular Imaging: Reality or Future? [PDF]

, 2021
The rapidly developing field of molecular medical imaging focuses on specific visualization of (patho)physiological processes through the application of imaging agents (IAs) in multiple clinical modalities.
Elsinga, Philip H., Bohmer, Verena I., Szymanski, Wiktor, Feringa, Ben L.   +3 more
core   +1 more source

Molecular imaging biomarkers for immune checkpoint inhibitor therapy

Theranostics, 2020
Immune checkpoint inhibitors (ICIs) have substantially changed the field of oncology over the past few years. ICIs offer an alternative treatment strategy by exploiting the patients' immune system, resulting in a T cell mediated anti-tumor response ...
P. P. van de Donk, Laura Kist de Ruijter, M. L. Lub-de Hooge, A. Brouwers, A. J. van der Wekken, S. Oosting, R. Fehrmann, D. D. de Groot, E. D. de Vries   +8 more
semanticscholar   +1 more source

Long-term Ashtanga yoga practice decreases medial temporal and brainstem glucose metabolism in relation to years of experience

EJNMMI Research, 2020
Background Yoga is increasingly popular worldwide with several physical and mental benefits, but the underlying neurobiology remains unclear. Whereas many studies have focused on pure meditational aspects, the triad of yoga includes meditation, postures,
June van Aalst, Jenny Ceccarini, Georg Schramm, Donatienne Van Weehaeghe, Ahmadreza Rezaei, Koen Demyttenaere, Stefan Sunaert, Koen Van Laere   +7 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Darwinian molecular imaging [PDF]

European Journal of Nuclear Medicine and Molecular Imaging, 2009
On 12 February 2009, we celebrated the 200th anniversaryof Charles Darwin’s birthday. His theory of evolutionthrough natural selection [1] is a most famous biologicalconcept, with a notoriety as wide as Albert Einstein’sconcept of relativity in physics.
Bertrand, Tavitian, Uwe, Haberkorn
openaire   +2 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source