Results 181 to 190 of about 39,713 (240)

Novel Sulfur‐Rich Polymers from Inverse Vulcanization as Functional Building Blocks for Photonics

open access: yesMacromolecular Rapid Communications, EarlyView.
Isopropenyl aromatic comonomers, in particular novel 2,7‐diisopropenylfluorene and 2,8‐diisopropenyldibenzothiophene, synthesized by sustainable, facile, single‐step SMCCR from available brominated substrates are exploited in the Inverse Vulcanization process to obtain functional Sulfur‐rich macromolecular materials.
Raimondo Insogna   +7 more
wiley   +1 more source

Progress on the Application of Polymers of Intrinsic Microporosity for the Adsorption of Organic Contaminants

open access: yesChemistryOpen, EarlyView.
The pictorial illustration of the applications of polymers of intrinsic microporosity extraordinary porous organic polymers with high surface areas, pore radii, pore volumes, high permeability, high diffusivity, high selectivity, and high thermal stability, as suitable filters or purifiers for water contaminated with pharmaceutical and organic dyes ...
Martins O. Omorogie
wiley   +1 more source

Multiple‐Use Microplate Assay for Submicromolar Ultra High‐Throughput Separation of Amines Based on their Degree of Substitution

open access: yesChemistryOpen, EarlyView.
A reusable microplate platform for ultra‐high‐throughput, submicromolar separation of protonated amines – including alkyl‐, aryl‐, and aralkyl‐types – using a tris(pyridino)‐crown ether selector was introduced; the method enables rapid, zero‐energy, parallel purification fully compatible with automated synthesis workflows.
Panna Vezse   +3 more
wiley   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear   +7 more
wiley   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

open access: yesPediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil   +2 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

open access: yesPhytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam   +14 more
wiley   +1 more source

Moist convection and radiative cooling: Dynamical response and scaling

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
The mechanism that sets the updraught velocities in deep convective clouds is studied here using cloud‐resolving model simulations in radiative–convective equilibrium. We show that, for simulations with vastly different rates of radiative cooling and surface temperatures, the buoyancy in clouds remains remarkably constant (histogram shown here).
Lokahith Agasthya, Caroline Muller
wiley   +1 more source

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