Results 1 to 10 of about 17,518 (240)
The Role of Long Non-coding RNAs in Human Imprinting Disorders: Prospective Therapeutic Targets [PDF]
Frontiers in Cell and Developmental Biology, 2021 Genomic imprinting is a term used for an intergenerational epigenetic inheritance and involves a subset of genes expressed in a parent-of-origin-dependent way.
Jianjian Li, Tingxuan Wang
exaly +4 more sources
Imprinting disorders as a window to understand pediatric feeding disorders [PDF]
Orphanet Journal of Rare DiseasesImprinting disorders are a group of rare congenital disorders characterized by common clinical features that affect growth, development, metabolism, and shared molecular abnormalities [1].
Juliette Salles +4 more
doaj +4 more sources
Association of four imprinting disorders and ART [PDF]
Clinical Epigenetics, 2019 Background Human-assisted reproductive technologies (ART) are a widely accepted treatment for infertile couples. At the same time, many studies have suggested the correlation between ART and increased incidences of normally rare imprinting disorders such
Hiromitsu Hattori +10 more
doaj +5 more sources
Chromosome 15 Imprinting Disorders: Genetic Laboratory Methodology and Approaches [PDF]
Frontiers in Pediatrics, 2020 Chromosome 15 imprinting disorders include Prader-Willi (PWS) and Angelman (AS) syndromes, which are caused by absent expression from the paternal and maternal alleles in the chromosome 15q11. 2–q13 region, respectively.
Jessica Duis, , Duis Jessica
exaly +4 more sources
Role of ART in Imprinting Disorders [PDF]
Seminars in Reproductive Medicine, 2012 Assisted reproductive technologies (ART) offer revolutionary infertility treatments for millions of childless couples around the world. Currently, ART accounts for 1 to 3% of annual births in industrialized countries and continues to expand rapidly. Except for an increased incidence of premature births, these technologies are considered safe.
Lawrence Layman, Ali Eroglu
exaly +5 more sources
The origin of imprinting defects in Temple syndrome and comparison with other imprinting disorders [PDF]
Epigenetics, 2018 Temple syndrome (TS14) is a rare imprinting disorder caused by genetic and epigenetic alterations on chromosome 14q32. A subset of these patients shows an imprinting defect (ID) where the paternal allele harbors a maternal epigenotype thus silencing the ...
Jasmin Beygo +6 more
doaj +6 more sources
Imprinting disorders in humans: a review. [PDF]
Curr Opin Pediatr, 2020 Purpose of review Mammals have two complete sets of chromosomes, one from each parent with equal autosomal gene expression. Less than one percentage of human genes are imprinted or show expression from only one parent without changing gene structure, usually by DNA methylation, but reversible in gametogenesis.
Butler MG.
europepmc +4 more sources
Imprinting disorders and assisted reproductive technology [PDF]
Fertility and Sterility, 2009 To review currently available literature on the association between imprinting disorders (Beckwith-Wiedemann syndrome [BWS], Angelman syndrome [AS] and retinoblastoma) and assisted reproductive technology (ART) in humans.Publications related to imprinting/epigenetic disorders including BWS, AS, and retinoblastoma with ART, as well as articles ...
James Segars, Alan Decherney
exaly +8 more sources
Novel epigenetic molecular therapies for imprinting disorders. [PDF]
Mol Psychiatry, 2023 AbstractGenomic imprinting disorders are caused by the disruption of genomic imprinting processes leading to a deficit or increase of an active allele. Their unique molecular mechanisms underlying imprinted genes offer an opportunity to investigate epigenetic-based therapy for reactivation of an inactive allele or reduction of an active allele. Current
Wang SE, Jiang YH.
europepmc +3 more sources
Association of Assisted Reproductive Technology Treatments with Imprinting Disorders [PDF]
Global Medical Genetics, 2021 Assisted reproductive technology (ART) is a broad field in infertility that encompasses different types of treatments. These revolutionary treatment methods aimed to aid infertile or subfertile couples. Treatment was expanded exponentially, as 1 to 3% of
T. Kopca, Pinar Tulay
doaj +2 more sources