Results 1 to 10 of about 24,778 (138)
Do social insects support Haig's kin theory for the evolution of genomic imprinting? [PDF]
Epigenetics, 2017 Although numerous imprinted genes have been described in several lineages, the phenomenon of genomic imprinting presents a peculiar evolutionary problem.
Mirko Pegoraro +3 more
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Retrotransposon silencing by DNA methylation can drive mammalian genomic imprinting. [PDF]
PLoS Genetics, 2007 Among mammals, only eutherians and marsupials are viviparous and have genomic imprinting that leads to parent-of-origin-specific differential gene expression. We used comparative analysis to investigate the origin of genomic imprinting in mammals. PEG10 (
Shunsuke Suzuki +12 more
doaj +4 more sources
, 2021 AbstractA typical cell contains two sets of chromosomes: one that was inherited from the mother, the other from the father. Usually, autosomal alleles are expressed at similar levels from the maternally and paternally inherited chromosomes. This chapter is dedicated to an exception of this rule: the expression of genes that are regulated by genomic ...
Sharvari Deshpande +2 more
+4 more sources
Trisomy 21 alters DNA methylation in parent-of-origin-dependent and independent manners [PDF]
, 2016 The supernumerary chromosome 21 in Down syndrome differentially affects the methylation statuses at CpG dinucleotide sites and creates genome-wide transcriptional dysregulation of parental alleles, ultimately causing diverse pathologies.
Alves da Silva, Antônio Francisco +12 more
core +9 more sources
Mammalian Genomic Imprinting [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Normal mammalian development requires a maternal and paternal contribution, which is attributed to imprinted genes, or genes that are expressed from a single parental allele. Approximately 100 imprinted genes have been reported in mammals thus far. Imprinted genes are controlled by cis-acting regulatory elements, termed imprinting control regions (ICRs)
Marisa S, Bartolomei +1 more
openaire +2 more sources
Frontiers in Genetics, 2022 Genomic imprinting is an epigenetic phenomenon defined as the silencing of an allele, at least partially, at a given locus based on the sex of the transmitting parent.
David Kenny +5 more
doaj +1 more source
Anales espanoles de pediatria, 1998 Abstract Certain genes demonstrate a parent-of-origin effect in their expression. This parent-of-origin effect occurs because these genes are modified during their transmission via oocytes or spermatocytes. The process of germ cell-specific modification of a gene is known as genomic imprinting, a term that was coined by Helen Crouse.
M, Moreno García, E, Barreiro Miranda
+6 more sources
Open Access Macedonian Journal of Medical Sciences, 2016 BACKGROUND: Genomic imprinting is the inheritance out of Mendelian borders. Many of inherited diseases and human development violates Mendelian law of inheritance, this way of inheriting is studied by epigenetics.AIM: The aim of this review is to analyze current opinions and options regarding to this way of inheriting.RESULTS: Epigenetics shows that ...
Bajrami, Emirjeta, Spiroski, Mirko
openaire +5 more sources
Genomic Imprinting in Plants [PDF]
Epigenetics, 2008 Genomic imprinting attracted particular attention in the 1980’s following the discovery that the parental origin of genetic information is essential for normal development of eutherians1,2, for review see3. The term imprinting was first introduced in the 1960s to describe the elimination of the paternal chromosomes during spermatogenesis in the Sciarid
Olivier, Garnier +2 more
openaire +3 more sources
Aberrations of Genomic Imprinting in Glioblastoma Formation
Frontiers in Oncology, 2021 In human glioblastoma (GBM), the presence of a small population of cells with stem cell characteristics, the glioma stem cells (GSCs), has been described. These cells have GBM potential and are responsible for the origin of the tumors.
Anna Lozano-Ureña +8 more
doaj +1 more source