Background Genomic imprinting is an epigenetic phenomenon mainly occurs in endosperm of flowering plants. Genome-wide identification of imprinted genes have been completed in several dicot Cruciferous plant and monocot crops.
Zhichao Zhang +12 more
doaj +1 more source
Methylation of the imprinted GNAS1 gene in cell-free plasma DNA : equal steady-state quantities of methylated and unmethylated DNA in plasma [PDF]
Background Genomic DNA sequences in cell-free plasma are biomarkers of cancer prognosis, where characteristic changes in methylation of tumour suppressor or oncogene DNA regions are indicative of changes in gene activity.
Alberry +26 more
core +1 more source
Sex dependent imprinting effects on complex traits in mice
Background Genomic imprinting is an epigenetic source of variation in quantitative traits that results from monoallelic gene expression, where commonly either only the paternally- or the maternally-derived allele is expressed.
Leamy Larry J +3 more
doaj +1 more source
The Role of Long Non-coding RNAs in Human Imprinting Disorders: Prospective Therapeutic Targets
Genomic imprinting is a term used for an intergenerational epigenetic inheritance and involves a subset of genes expressed in a parent-of-origin-dependent way.
Tingxuan Wang +4 more
doaj +1 more source
Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis [PDF]
© The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Xu, X., Li, G., Li, C., Zhang, J., Wang, Q., Simmons, D. K., Chen, X., Wijesena, N., Zhu, W., Wang, Z.,
Aluru, Neelakanteswar +20 more
core +2 more sources
Livestock species as emerging models for genomic imprinting
Genomic imprinting is an epigenetically-regulated process of central importance in mammalian development and evolution. It involves multiple levels of regulation, with spatio-temporal heterogeneity, leading to the context-dependent and parent-of-origin ...
Jean-Noël Hubert +3 more
doaj +1 more source
Genomic imprinting has been thought to play an important role in seed development in flowering plants. Seed in a flowering plant normally contains diploid embryo and triploid endosperm.
Cui, Yuehua, Li, Gengxin
core +1 more source
Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions. [PDF]
BackgroundCTCF and BORIS (CTCFL), two paralogous mammalian proteins sharing nearly identical DNA binding domains, are thought to function in a mutually exclusive manner in DNA binding and transcriptional regulation.ResultsHere we show that these two ...
Boukaba, Abdelhalim +15 more
core +3 more sources
Characterisation of marsupial
Background Genomic imprinting causes parent-of-origin specific gene expression by differential epigenetic modifications between two parental genomes. We previously reported that there is no evidence of genomic imprinting of CDKN1C in the KCNQ1 domain in ...
Shaw Geoffrey +4 more
doaj +1 more source
Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort [PDF]
Data from epidemiological and animal model studies suggest that nutrition during pregnancy may affect the health status of subsequent generations. These transgenerational effects are now being explained by disruptions at the level of the epigenetic ...
A Kerjean +68 more
core +3 more sources

