Results 31 to 40 of about 33,268 (235)
BMC Plant Biology, 2021 Background Genomic imprinting is an epigenetic phenomenon mainly occurs in endosperm of flowering plants. Genome-wide identification of imprinted genes have been completed in several dicot Cruciferous plant and monocot crops.
Zhichao Zhang +12 more
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Sex dependent imprinting effects on complex traits in mice
BMC Evolutionary Biology, 2008 Background Genomic imprinting is an epigenetic source of variation in quantitative traits that results from monoallelic gene expression, where commonly either only the paternally- or the maternally-derived allele is expressed.
Leamy Larry J +3 more
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The Role of Long Non-coding RNAs in Human Imprinting Disorders: Prospective Therapeutic Targets
Frontiers in Cell and Developmental Biology, 2021 Genomic imprinting is a term used for an intergenerational epigenetic inheritance and involves a subset of genes expressed in a parent-of-origin-dependent way.
Tingxuan Wang +4 more
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Mammalian Genomic Imprinting [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Normal mammalian development requires a maternal and paternal contribution, which is attributed to imprinted genes, or genes that are expressed from a single parental allele. Approximately 100 imprinted genes have been reported in mammals thus far. Imprinted genes are controlled by cis-acting regulatory elements, termed imprinting control regions (ICRs)
Marisa S, Bartolomei +1 more
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Characterisation of marsupial
BMC Evolutionary Biology, 2011 Background Genomic imprinting causes parent-of-origin specific gene expression by differential epigenetic modifications between two parental genomes. We previously reported that there is no evidence of genomic imprinting of CDKN1C in the KCNQ1 domain in ...
Shaw Geoffrey +4 more
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The Evolution of Genomic Imprinting [PDF]
Genetics, 1996 Abstract In some mammalian genes, the paternally and maternally derived alleles are expressed differently: this phenomenon is called genomic imprinting. Here we study the evolution of imprinting using multivariate quantitative genetic models to examine the feasibility of the genetic conflict hypothesis.
A, Mochizuki, Y, Takeda, Y, Iwasa
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, 2021 AbstractA typical cell contains two sets of chromosomes: one that was inherited from the mother, the other from the father. Usually, autosomal alleles are expressed at similar levels from the maternally and paternally inherited chromosomes. This chapter is dedicated to an exception of this rule: the expression of genes that are regulated by genomic ...
Renato Paro +3 more
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Genomic imprinting beyond DNA methylation: a role for maternal histones
Genome Biology, 2017 Inheritance of DNA methylation states from gametes determines genomic imprinting in mammals. A new study shows that repressive chromatin in oocytes can also confer imprinting.
Courtney W. Hanna, Gavin Kelsey
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source