Results 51 to 60 of about 24,778 (138)

Thermal imprinting modifies adult stress and innate immune responsiveness in the teleost sea bream [PDF]

, 2017
The impact of thermal imprinting on the plasticity of the hypothalamic-pituitary-interrenal (HPI) axis and stress response in an adult ectotherm, the gilthead sea bream (Sparus aurata, L.), during its development was assessed.
A Costa, Rita, Andree, Karl B., Cardoso, João CR, Estevez, Alicia, Gisbert, Enric, Mateus, Ana, Power, Deborah   +6 more
core   +1 more source

Retinoblastoma and its binding partner MSI1 control imprinting in Arabidopsis. [PDF]

PLoS Biology, 2008
Parental genomic imprinting causes preferential expression of one of the two parental alleles. In mammals, differential sex-dependent deposition of silencing DNA methylation marks during gametogenesis initiates a new cycle of imprinting. Parental genomic
Pauline E Jullien, Assaf Mosquna, Mathieu Ingouff, Tadashi Sakata, Nir Ohad, Frédéric Berger   +5 more
doaj   +1 more source

Evolutionary lineage-specific genomic imprinting at the ZNF791 locus.

PLoS Genetics
Genomic imprinting is an epigenetic process that results in parent-of-origin effects on mammalian development and growth. Research on genomic imprinting in domesticated animals has lagged due to a primary focus on orthologs of mouse and human imprinted ...
Jinsoo Ahn, In-Sul Hwang, Mi-Ryung Park, Milca Rosa-Velazquez, In-Cheol Cho, Alejandro E Relling, Seongsoo Hwang, Kichoon Lee   +7 more
doaj   +1 more source

A comprehensive overview of genomic imprinting in breast and its deregulation in cancer

Nature Communications, 2018
In growth and development genomic imprinting is important in regulating gene expression. Here, the authors study loss of imprinting (LOI) in cancer, developing a mixture model to detect monoallelically expressed loci without genotyping data - applying ...
Tine Goovaerts, Sandra Steyaert, Chari A. Vandenbussche, Jeroen Galle, Olivier Thas, Wim Van Criekinge, Tim De Meyer   +6 more
doaj   +1 more source

Genomic imprinting in human placentation

Reproductive Medicine and Biology, 2022
Background Genomic imprinting (GI) is a mammalian‐specific epigenetic phenomenon that has been implicated in the evolution of the placenta in mammals.
Eri H. Kobayashi, Shun Shibata, Akira Oike, Norio Kobayashi, Hirotaka Hamada, Hiroaki Okae, Takahiro Arima   +6 more
doaj   +1 more source

Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]

, 2011
: Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Cox, SE, Dominguez-Salas, P, Hennig, BJ, Moore, SE, Prentice, AM   +4 more
core   +4 more sources

Mosaic Analysis with Double Markers Reveals Cell-Type-Specific Paternal Growth Dominance

Cell Reports, 2013
Genomic imprinting leads to preferred expression of either the maternal or paternal alleles of a subset of genes. Imprinting is essential for mammalian development, and its deregulation causes many diseases.
Simon Hippenmeyer, Randy L. Johnson, Liqun Luo   +2 more
doaj   +1 more source

Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage. [PDF]

, 2019
One fundamental but understudied mechanism of gene regulation in disease is allele-specific expression (ASE), the preferential expression of one allele.
A Chess, A de la Chapelle, A Gimelbrant, A Hogart, A McKenna, A Mortazavi, AA Adegbola, AL Oberg, AM Veerappa, B DeVeale, B Howie, B Langmead, B Tycko, C Fuchsberger, C Gicquel, C Gregg, C Lee, CA de Leeuw, CCY Wong, Changhoon Lee, Cross-Disorder Group of the Psychiatric Genomics Consortium., D Kim, Daniel H. Geschwind, DH Geschwind, E Ben-David, E Eden, E Eden, E Gardiner, EH Cook Jr., Eleazar Eskin, EM Quinn, Eun Yong Kang, EY Kang, F Supek, GT Consortium, GV Kryukov, H Li, HA Scoles, I Iossifov, I Voineagu, J Cavaille, J Cavaille, J Grove, JC Darnell, JF Degner, JK Pickrell, KR Kukurba, M Elsabbagh, M Meguro-Horike, Michael J. Gandal, N Mukherjee, NN Parikshak, NN Parikshak, PH Sudmant, PS Bazeley, R Karlic, S Anders, S Kehr, S Kishore, S Nardone, S Purcell, Schizophrenia Working Group of the Psychiatric Genomics Consortium., SE Castel, SJ Sanders, SM Weyn-Vanhentenryck, T Hulsen, V Savova, Y Zhang, YE Wu   +68 more
core   +1 more source

Syndromic Disorders Caused by Disturbed Human Imprinting

JCRPE, 2020
Imprinting disorders are a group of congenital diseases caused by dysregulation of genomic imprinting, affecting prenatal and postnatal growth, neurocognitive development, metabolism and cancer predisposition.
Diana Carli, Evelise Riberi, Giovanni Battista Ferrero, Alessandro Mussa   +3 more
doaj   +1 more source

Birth seasonality studies in a large Prader-Willi syndrome cohort. [PDF]

, 2019
Prader-Willi syndrome (PWS) is generally due to sporadic paternal deletions of the chromosome 15q11-q13 region followed by maternal disomy 15. Advanced maternal age is more commonly seen in those with maternal disomy 15. Environmental factors (e.g., drug
Butler, Merlin G, Driscoll, Daniel J, Dykens, Elisabeth, Gold, June Anne, Kimonis, Virginia, Miller, Jennifer L, Tamura, Roy   +6 more
core   +1 more source