Results 71 to 80 of about 33,170 (247)

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Mechanisms of genomic imprinting

Current Opinion in Genetics & Development, 1999
A small number of mammalian genes undergo the process of genomic imprinting whereby the expression level of the alleles of a gene depends upon their parental origin. In the past year, attention has focused on the mechanisms that determine parental-specific expression patterns.
Department of Molecular Genetics and Microbiology, The Center for Mammalian Genetics and the University of Florida Brain Institute, University of Florida College of Medicine, Gainesville, Florida 32610, USA ( host institution ), Brannan, Camilynn I, Bartolomei, Marisa S   +2 more
openaire   +3 more sources

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Influence of Exogenous Factors on Genomic Imprinting 3. The Impact of Assisted Reproductive Technologies

Zdorovʹe Rebenka, 2016
The analytical review demonstrated the impact of assisted reproductive technologies on genomic imprinting of a child. It is shown that assisted reproductive technologies have a risk of intrauterine growth retardation and imprinting-associated Beckwith ...
A.E. Abaturov
doaj   +1 more source

Primary Pulmonary Epithelioid Inflammatory Myofibroblastic Sarcoma With SQSTM1::ALK Fusion

Diagnostic Cytopathology, EarlyView.
ABSTRACT Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is a rare and aggressive variant of inflammatory myofibroblastic tumor (IMT) characterized by epithelioid morphology, atypical features, ALK rearrangements, and early metastatic potential.
Havva Gokce Terzioglu, Phillip McMullen, Güliz A. Barkan   +2 more
wiley   +1 more source

AIMER: A SNP-independent software for identifying imprinting-like allelic methylated regions from DNA methylome

Computational and Structural Biotechnology Journal
Genomic imprinting is essential for mammalian growth and embryogenesis. High-throughput bisulfite sequencing accompanied with parental haplotype-specific information allows analysis of imprinted genes and imprinting control regions (ICRs) on a large ...
Yanrui Luo, Tong Zhou, Deng Liu, Fan Wang, Qian Zhao   +4 more
doaj   +1 more source

The Landscape of Genomic Imprinting at the Porcine SGCE/PEG10 Locus from Methylome and Transcriptome of Parthenogenetic Embryos

G3: Genes, Genomes, Genetics, 2020
In mammals, imprinted genes often exist in the form of clusters in specific chromosome regions. However, in pigs, genomic imprinting of a relatively few genes and clusters has been identified, and genes within or adjacent to putative imprinted clusters ...
Jinsoo Ahn, In-Sul Hwang, Mi-Ryung Park, In-Cheol Cho, Seongsoo Hwang, Kichoon Lee   +5 more
doaj   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Evolution of the CDKN1C-KCNQ1 imprinted domain

BMC Evolutionary Biology, 2008
Background Genomic imprinting occurs in both marsupial and eutherian mammals. The CDKN1C and IGF2 genes are both imprinted and syntenic in the mouse and human, but in marsupials only IGF2 is imprinted.
Shaw Geoff, Gehring Helen M, Pask Andrew J, Ager Eleanor I, Renfree Marilyn B   +4 more
doaj   +1 more source

Long noncoding RNA functionality in imprinted domain regulation.

PLoS Genetics, 2020
Genomic imprinting is a parent-of-origin dependent phenomenon that restricts transcription to predominantly one parental allele. Since the discovery of the first long noncoding RNA (lncRNA), which notably was an imprinted lncRNA, a body of knowledge has ...
William A MacDonald, Mellissa R W Mann
doaj   +1 more source