Results 71 to 80 of about 24,778 (138)

Environment, epigenetics and neurodegeneration: Focus on nutrition in Alzheimer's disease [PDF]

, 2015
Many different environmental factors (nutrients, pollutants, chemicals, physical activity, lifestyle, physical and mental stress) can modulate epigenetic markers in the developing and adult organism. Epigenetics, in turn, can cause and is associated with
FUSO, ANDREA, LUCARELLI, Marco, NICOLIA, Vincenzina   +2 more
core   +3 more sources

Genomic imprinting and assisted reproduction

Reproductive Health, 2004
Imprinted genes exhibit a parent-of-origin specific pattern of expression. Such genes have been shown to be targets of molecular defects in particular genetic syndromes such as Beckwith-Wiedemann and Angelman syndromes. Recent reports have raised concern
Chaillet J Richard, Paoloni-Giacobino Ariane   +1 more
doaj   +1 more source

Exercise epigenetics and the foetal origins of disease [PDF]

, 2014
Exercise epigenetics is a nascent area of research with vast health implications (e.g., from the treatment of obesity-related diseases to beneficially decoupling epigenetic and chronological age).
Dale E, Thomas EW Chalk, William M Brown
core   +1 more source

Influence of Exogenous Factors on Genomic Imprinting 3. The Impact of Assisted Reproductive Technologies

Zdorovʹe Rebenka, 2016
The analytical review demonstrated the impact of assisted reproductive technologies on genomic imprinting of a child. It is shown that assisted reproductive technologies have a risk of intrauterine growth retardation and imprinting-associated Beckwith ...
A.E. Abaturov
doaj   +1 more source

A global disorder of imprinting in the human female germ line [PDF]

, 2002
Imprinted genes are expressed differently depending on whether they are carried by a chromosome of maternal or paternal origin. Correct imprinting is established by germline-specific modifications; failure of this process underlies several inherited ...
A Kerjean, BE Hayward, BE Hayward, BE Hayward, Bruce E. Hayward, D Bourc’his, David T. Bonthron, Eamonn Sheridan, Hannah Judson, J Liu, J Liu, JS Sutcliffe, K Buiting, L Strain, M Kamiya, MN Helwani, MP Lee, NJ Smilinich, O El-Maarri, R Shemer, RA Fisher, RJ Gardner, S Engemann, SJ Clark, SK Murphy, T Kajii, T Kaneko-Ishino, T Ohta, W Reik, W Reik, YB Moglabey   +30 more
core   +1 more source

AIMER: A SNP-independent software for identifying imprinting-like allelic methylated regions from DNA methylome

Computational and Structural Biotechnology Journal
Genomic imprinting is essential for mammalian growth and embryogenesis. High-throughput bisulfite sequencing accompanied with parental haplotype-specific information allows analysis of imprinted genes and imprinting control regions (ICRs) on a large ...
Yanrui Luo, Tong Zhou, Deng Liu, Fan Wang, Qian Zhao   +4 more
doaj   +1 more source

The Landscape of Genomic Imprinting at the Porcine SGCE/PEG10 Locus from Methylome and Transcriptome of Parthenogenetic Embryos

G3: Genes, Genomes, Genetics, 2020
In mammals, imprinted genes often exist in the form of clusters in specific chromosome regions. However, in pigs, genomic imprinting of a relatively few genes and clusters has been identified, and genes within or adjacent to putative imprinted clusters ...
Jinsoo Ahn, In-Sul Hwang, Mi-Ryung Park, In-Cheol Cho, Seongsoo Hwang, Kichoon Lee   +5 more
doaj   +1 more source

Evolution of the CDKN1C-KCNQ1 imprinted domain

BMC Evolutionary Biology, 2008
Background Genomic imprinting occurs in both marsupial and eutherian mammals. The CDKN1C and IGF2 genes are both imprinted and syntenic in the mouse and human, but in marsupials only IGF2 is imprinted.
Shaw Geoff, Gehring Helen M, Pask Andrew J, Ager Eleanor I, Renfree Marilyn B   +4 more
doaj   +1 more source

Long noncoding RNA functionality in imprinted domain regulation.

PLoS Genetics, 2020
Genomic imprinting is a parent-of-origin dependent phenomenon that restricts transcription to predominantly one parental allele. Since the discovery of the first long noncoding RNA (lncRNA), which notably was an imprinted lncRNA, a body of knowledge has ...
William A MacDonald, Mellissa R W Mann
doaj   +1 more source

The Imprinted Retrotransposon-Like Gene PEG11 (RTL1) Is Expressed as a Full-Length Protein in Skeletal Muscle from Callipyge Sheep [PDF]

peer-reviewedMembers of the Ty3-Gypsy retrotransposon family are rare in mammalian genomes despite their abundance in invertebrates and some vertebrates.
Bidwell, Christopher A., Byrne, Keren, Cockett, Noelle E., Colgrave, Michelle L., Fleming-Waddell, Jolena N., Lynn, David J, Pearson, Roger, Tellam, Ross L, Vuocolo, Tony   +8 more
core   +1 more source