Results 21 to 30 of about 33,170 (247)

Parent-of-origin effects cause genetic variation in pig performance traits

open access: yesAnimal, 2010
In order to assess the relative importance of genomic imprinting for the genetic variation of traits economically relevant for pork production, a data set containing 21 209 records from Large White pigs was analysed.
N. Neugebauer, H. Luther, N. Reinsch
doaj   +1 more source

Placental imprinting: Emerging mechanisms and functions.

open access: yesPLoS Genetics, 2020
As the maternal-foetal interface, the placenta is essential for the establishment and progression of healthy pregnancy, regulating both foetal growth and maternal adaptation to pregnancy.
Courtney W Hanna
doaj   +1 more source

The Evolutionary Advantage in Mammals of the Complementary Monoallelic Expression Mechanism of Genomic Imprinting and Its Emergence From a Defense Against the Insertion Into the Host Genome

open access: yesFrontiers in Genetics, 2022
In viviparous mammals, genomic imprinting regulates parent-of-origin-specific monoallelic expression of paternally and maternally expressed imprinted genes (PEGs and MEGs) in a region-specific manner.
Tomoko Kaneko-Ishino, Fumitoshi Ishino
doaj   +1 more source

Genomic Imprinting in Mammals [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2014
Genomic imprinting affects a subset of genes in mammals and results in a monoallelic, parental-specific expression pattern. Most of these genes are located in clusters that are regulated through the use of insulators or long noncoding RNAs (lncRNAs). To distinguish the parental alleles, imprinted genes are epigenetically marked in gametes at imprinting
Denise P, Barlow, Marisa S, Bartolomei
openaire   +2 more sources

Imprinting and its disorders in evolutionary perspective

open access: yesActa Medica Lituanica, 2014
Bacground. Genomic imprinting is one of the best-studied epigenetic phenomena involving all the main epigenetic processes. Recent investigations led to a huge expansion of knowledge in this field and changed some established paradigms regarding ...
Birutė Tumienė   +2 more
doaj   +1 more source

Zfp57 mutant ES cell lines directly derived from blastocysts

open access: yesStem Cell Research, 2016
Zfp57 is a master regulator of genomic imprinting in mouse embryos. To further test its functions, we have derived multiple Zfp57 mutant ES clones directly from mouse blastocysts.
Ho-Tak Lau, Lizhi Liu, Xiajun Li
doaj   +1 more source

Genomic imprinting in diabetes [PDF]

open access: yesGenome Medicine, 2010
Genomic imprinting refers to a class of transmissible genetic effects in which the expression of the phenotype in the offspring depends on the parental origin of the transmitted allele. The DNA from one parent may be epigenetically modified so that only a single allele of the imprinted gene is expressed in the offspring.
Mitchell, Braxton D, Pollin, Toni I
openaire   +2 more sources

Technical advances contribute to the study of genomic imprinting.

open access: yesPLoS Genetics, 2019
Genomic imprinting in mammals was discovered over 30 years ago through elegant embryological and genetic experiments in mice. Imprinted genes show a monoallelic and parent of origin-specific expression pattern; the development of techniques that can ...
Yuanyuan Li, Jinsong Li
doaj   +1 more source

Genomic imprinting and genetic effects on muscle traits in mice

open access: yesBMC Genomics, 2012
Background Genomic imprinting refers to parent-of-origin dependent gene expression caused by differential DNA methylation of the paternally and maternally derived alleles.
Kärst Stefan   +3 more
doaj   +1 more source

Epigenetic modifications potentially controlling the allelic expression of imprinted genes in sunflower endosperm

open access: yesBMC Plant Biology, 2021
Background Genomic imprinting is an epigenetic phenomenon mainly occurs in endosperm of flowering plants. Genome-wide identification of imprinted genes have been completed in several dicot Cruciferous plant and monocot crops.
Zhichao Zhang   +12 more
doaj   +1 more source

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