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Mechanisms of genomic imprinting [PDF]
Growth Hormone & IGF Research, 2000 Imprinted genes represent a curious defiance of normal Mendelian genetics. Mammals inherit two complete sets of chromosomes, one from the mother and one from the father, and most autosomal genes will be expressed from both the maternal and the paternal alleles.
A R, Hoffman, T H, Vu, J, Hu
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Retrotransposon silencing by DNA methylation can drive mammalian genomic imprinting. [PDF]
PLoS Genetics, 2007 Among mammals, only eutherians and marsupials are viviparous and have genomic imprinting that leads to parent-of-origin-specific differential gene expression. We used comparative analysis to investigate the origin of genomic imprinting in mammals. PEG10 (
Shunsuke Suzuki +12 more
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Effects of reprogramming on genomic imprinting and the application of pluripotent stem cells
Stem Cell Research, 2019 Pluripotent stem cells are considered to be the ideal candidates for cell-based therapies in humans. In this regard, both nuclear transfer embryonic stem (ntES) cells and induced pluripotent stem (iPS) cells are particularly advantageous because patient ...
Xiajun Li +3 more
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Open Access Macedonian Journal of Medical Sciences, 2016 BACKGROUND: Genomic imprinting is the inheritance out of Mendelian borders. Many of inherited diseases and human development violates Mendelian law of inheritance, this way of inheriting is studied by epigenetics.AIM: The aim of this review is to analyze current opinions and options regarding to this way of inheriting.RESULTS: Epigenetics shows that ...
Bajrami, Emirjeta, Spiroski, Mirko
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Archives of Disease in Childhood, 1990 In the last few years, the importance of genomic imprinting as a basic biological phenomenon has become clear. Work from different areas has demonstrated that parent-of-origin differences in phenotype occur on a regular basis. This article summarizes some of the recent advances made in this field.
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Genomic Imprinting Absent in Drosophila melanogaster Adult Females
Cell Reports, 2012 Genomic imprinting occurs when expression of an allele differs based on the sex of the parent that transmitted the allele. In D. melanogaster, imprinting can occur, but its impact on allelic expression genome-wide is unclear.
Joseph D. Coolon +4 more
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Cynomolgus-rhesus hybrid macaques serve as a platform for imprinting studies
The Innovation, 2023 Genomic imprinting can lead to allele-specific expression (ASE), where one allele is preferentially expressed more than the other. Perturbations in genomic imprinting or ASE genes have been widely observed across various neurological disorders, notably ...
Zongyang Lu +12 more
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Genomic imprinting in Singapore
EMBO reports, 2009 The EMBO Workshop on Genomic Imprinting took place between 21 and 24 September 2008, in Singapore, and was organized by F. Berger, M. Bartolomei and R. Feil. This painting, entitled ‘Back of Telok Ayer Street 2007’ and painted by C. Ek Kay, was the image included in the meeting poster.
Loppin, Benjamin, Oakey, Rebecca
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Genomic imprinting effects on complex traits in domesticated animal species
Frontiers in Genetics, 2015 Monoallelically expressed genes that exert their phenotypic effect in a parent-of-origin specific manner are considered to be subject to genomic imprinting, the most well understood form of epigenetic regulation of gene expression in mammals.
Alan eO'Doherty +3 more
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PLoS ONE, 2015 Genomic imprinting is a phenomenon characterized by parent-of-origin-specific gene expression. While widely documented in viviparous mammals and plants, imprinting in oviparous birds remains controversial.
Qiong Wang +7 more
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