Results 81 to 90 of about 39,713 (240)

A Mini‐Spidroin Forms High‐Performance Artificial Spider Silk via Edge‐Cysteine–Locked β‐Sheet Assembly

Advanced Science, EarlyView.
Cysteine‐engineered mini‐spidroins (∼33 kDa) undergo phosphate‐induced liquid–liquid phase separation (LLPS), where disulfide bonds lock partially aligned polyA segments. Subsequent microfluidic spinning promotes directional β‐sheet crystallization, producing fibers with 531 MPa strength and 182 MJ/m3 toughness.
Min Li, Huan Chen, Qi Zhang, Xiaoyun Xu, Yini Zheng, Chunyu Lyu, Weibin Jia, Jun Fan, Fu‐Rong Chen, Wei Liu, Jinlian Hu   +10 more
wiley   +1 more source

NanoLoop: A Deep Learning Framework Leveraging Nanopore Sequencing for Chromatin Loop Prediction

Advanced Science, EarlyView.
Chromatin loops are central to gene regulation and 3D genome organization. Leveraging Nanopore sequencing's ability to jointly capture DNA sequence and methylation, we present NanoLoop, the first framework for genome‐wide chromatin loop prediction using Nanopore data.
Wenjie Huang, Li Tang, Matthew C. Hill, Yonghao Zhang, Jun Xie, Min Li   +5 more
wiley   +1 more source

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

Synthetic Receptors Decorated on Nanoparticles for Selective and Sensitive Glyphosate Detection

Photonic Sensors
Herein, an innovative glyphosate imprinted poly(hydroxyethyl methacrylate-N-methacroyl-(L)-phenylalanine methyl ester nanoparticles (MIP@NPs) based plasmonic nanosensor featured with high sensitivity and selectivity was constructed by using the molecular
Ilgım Gokturk, Mamajan Ovezova, Gaye Ezgi Yilmaz, Deniz Turkmen, Fatma Yilmaz, Adil Denizli   +5 more
doaj   +1 more source

Machine Learning‐Enhanced Analysis of Exosomal Surface Sialic Acid Using Surface‐Enhanced Raman Spectroscopy for Ovarian Cancer Diagnosis and Therapeutic Monitoring

Advanced Science, EarlyView.
Machine learning‐assisted surface‐enhanced Raman spectroscopy analysis of exosomal sialic acid for ovarian cancer diagnosis, as well as independent monitoring of exosomal sialic acid expression levels across different treatment periods, reveals a potential correlation with treatment response.
Lili Cong, Jiaqi Wang, Sijun Huang, Xiaxia Man, Yi Guo, Shuping Xu, Songling Zhang   +6 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Polyvinylidene Fluoride-Based Nanowire-Imprinted Membranes with High Flux for Efficient and Selective Separation of Artemisinin/Artemether

Molecules
A traditional phase transformation method is commonly used to prepare molecular imprinting membranes for selective separation. However, traditional molecularly imprinted polymers are mostly micron-sized particles, and the imprinting sites in their ...
Minjia Meng, Jiajia Ren, Chuanxun Zhang, Wanqi Du, Jixiang Wang   +4 more
doaj   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source

Ambient Stable Triboelectric Nanogenerator Based on Conductive Filler Modified Silicone Rubber with Gas Barrier Encapsulation for Footstep Energy Conversion

Advanced Science, EarlyView.
A humidity‐tolerant triboelectric nanogenerator is developed using conductive carbon black‐modified silicone rubber and a flame‐retardant gas barrier layer. The device efficiently harvests footstep energy while maintaining stable output under 30–90% RH and over 1 million cycles.
Yi Wei, Yushu Tian, Xiaokang Chen, Junfeng Chu, Junjie Wang, Xiangyu Chen, Wenjie Wu, Liqun Zhang   +7 more
wiley   +1 more source

Advances in Molecular Imprinting Technology for the Extraction and Detection of Quercetin in Plants. [PDF]

Polymers (Basel), 2023
Ye K, Xu S, Zhou Q, Wang S, Xu Z, Liu Z.
europepmc   +1 more source