Antibody CDR loops as ensembles in solution vs. canonical clusters from X-ray structures
mAbs, 2020 In the past decade, the relevance of antibodies as therapeutics has increased substantially. Therefore, structural and functional characterization, in particular of the complementarity-determining regions (CDRs), is crucial to the design and engineering ...
Monica L. Fernández-Quintero +4 more
doaj +1 more source
Halogen Bonding in Sulphonamide Co-Crystals: X···π Preferred over X···O/N?
Molecules, 2023 Sulphonamides have been one of the major pharmaceutical compound classes since their introduction in the 1930s. Co-crystallisation of sulphonamides with halogen bonding (XB) might lead to a new class of pharmaceutical-relevant co-crystals. We present the
Tobias Heinen +3 more
doaj +1 more source
Evolution of the Immunoglobulin Isotypes—Variations of Biophysical Properties among Animal Classes
Biomolecules, 2023 The adaptive immune system arose around 500 million years ago in jawed fish, and, since then, it has mediated the immune defense against pathogens in all vertebrates.
Nancy D. Pomarici +4 more
doaj +1 more source
Impact of peanut shells, olive pomace, and plaster on the dielectric properties of PA6
Chemical Physics Impact, 2023 Polyamide 6 (PA6) is among the most widely used technical polymers due to its excellent balance between performance and cost. The diversity of its applications reflects its main qualities (good mechanical properties, thermal stability, resistance to many
O. Oulidi +7 more
doaj +1 more source
Smart Ligands for Efficient 3d-, 4d- and 5d-Metal Single-Molecule Magnets and Single-Ion Magnets
Inorganics, 2020 There has been a renaissance in the interdisciplinary field of Molecular Magnetism since ~2000, due to the discovery of the impressive properties and potential applications of d- and f-metal Single-Molecule Magnets (SMMs) and Single-Ion Magnets (SIMs) or
Panagiota S. Perlepe +4 more
doaj +1 more source
Insights into DNA platination within unusual structural settings [PDF]
, 2011 2D [1H, 15N] HSQC NMR spectroscopy has been used to monitor reaction and product formation between [Pt(15NH3)2I2] and nucleic acids possessing irregular topologies and containing site specific phosphorothioate substitution in the phosphodiester backbone.
Harvie, Stephanie +2 more
core +2 more sources
Methyl Methacrylate Oligomerically-Modified Clay and its Poly (Methyl Methacrylate) Nanocomposites [PDF]
, 2005 A methyl methacrylate oligomerically-modified clay was used to prepare poly(methyl methacrylate) clay nanocomposites by melt blending and the effect of the clay loading level on the modified clay and corresponding nanocomposite was studied.
Jiang, David D. +2 more
core +2 more sources
Structural Basis of the Immunological Cross-Reactivity between Kiwi and Birch Pollen
Foods, 2023 Allergies related to kiwi consumption have become a growing health concern, with their prevalence on the rise. Many of these allergic reactions are attributed to cross-reactivity, particularly with the major allergen found in birch pollen.
Ricarda Zeindl +6 more
doaj +1 more source
Density functional theory in transition-metal chemistry: a self-consistent Hubbard U approach
, 2006 Transition-metal centers are the active sites for many biological and inorganic chemical reactions. Notwithstanding this central importance, density-functional theory calculations based on generalized-gradient approximations often fail to describe ...
C. Rovira +5 more
core +1 more source
Inorganic–organic nanocomposites of CdSe nanocrystals surface-modified with oligo- and poly(fluorene) moieties [PDF]
, 2011 We report a facile grafting-from strategy towards the synthesis of inorganic–organic composites of semiconductor nanocrystals and wide-bandgap polymers.
Adamczyk, Sylwia +12 more
core +1 more source