Results 41 to 50 of about 1,965,985 (318)

Intermolecular-Interaction-Driven Adaptive Remodeling: A Network Perspective on Plant Abiotic Stress Responses

Plants
Abiotic stresses, including drought, salinity, alkalinity, temperature extremes, flooding, heavy metals, and emerging pollutants, challenge plant growth and productivity by disturbing water relations, ion balance, redox homeostasis, membrane stability ...
Leidi Liu, Xiangfei Cheng, Yihua Xu, Lu Liu, Shuai Zhong, Xiaohua Chao, Yumin Chen, Chengde Yu, Chengming Fan, Changsong Zou   +9 more
doaj   +1 more source

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

eLife, 2021
The PcrA/UvrD helicase binds directly to RNA polymerase (RNAP) but the structural basis for this interaction and its functional significance have remained unclear.
Inigo Urrutia-Irazabal, James R Ault, Frank Sobott, Nigel J Savery, Mark S Dillingham   +4 more
doaj   +1 more source

Function of synthetic Hox transcription factors "in vivo" and the quantitative study of their molecular interactions with nuclear DNA at the single-molecule level in live cells [PDF]

, 2010
Over a century of research, invested in providing an answer to the fundamental question of how a single diploid cell constructs a whole organism, has placed Drosophila in the fore scene of developmental biology and has allowed us to merge the knowledge ...
Papadopoulos, Dimitrios
core   +1 more source

The Insignificance of Long-Distance Interactions for Molecular Frequencies. Analyses of Sparse Forceconstant Matrices [PDF]

, 2020
The experimentally observed group additivity of temperature dependent molecular properties of organic molecules i.e. the heat capacity, suggests that molecular vibrational frequencies primarily are determined by short-distance atomic interactions.
Gustav, Bojesen
core   +1 more source

Role in virulence of phospholipases, listeriolysin O and listeriolysin S from epidemic Listeria monocytogenes using the chicken embryo infection model

Veterinary Research, 2018
Most human listeriosis outbreaks are caused by Listeria monocytogenes evolutionary lineage I strains which possess four exotoxins: a phosphatidylinositol-specific phospholipase C (PlcA), a broad-range phospholipase C (PlcB), listeriolysin O (LLO) and ...
Juan J. Quereda, Christopher Andersson, Pascale Cossart, Jörgen Johansson, Javier Pizarro-Cerdá   +4 more
doaj   +1 more source

SepN is a septal junction component required for gated cell–cell communication in the filamentous cyanobacterium Nostoc

Nature Communications, 2022
The filamentous cyanobacterium Nostoc regulates communication between sister cells via a conformational change in septal junctions. Here, the authors identify and characterize protein SepN as a component of septal junctions, and highlight the importance ...
Ann-Katrin Kieninger, Piotr Tokarz, Ana Janović, Martin Pilhofer, Gregor L. Weiss, Iris Maldener   +5 more
doaj   +1 more source

Topology of molecular interaction networks [PDF]

BMC Systems Biology, 2013
Molecular interactions are often represented as network models which have become the common language of many areas of biology. Graphs serve as convenient mathematical representations of network models and have themselves become objects of study. Their topology has been intensively researched over the last decade after evidence was found that they share
Winterbach, W. (author), Van Mieghem, P. (author), Reinders, M. (author), Wang, H. (author), De Ridder, D. (author)   +4 more
openaire   +4 more sources

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

The molecular basis of co-evolution between Cladosporium fulvum and tomato [PDF]

, 2001
Cladosporium fulvum is a semi-biotrophic pathogen, which causes leaf mold of tomato (Lycopersicon spp.). In our laboratory this pathosystem serves as a model to study gene-for-gene interactions between plants and pathogenic fungi (Joosten & De Wit 1999).
Joosten, M.H.A.J., de Wit, P.J.G.M., van der Hoorn, R.A.L., Luderer, R., Leong, S.A., Triplett, E.W., van den Burg, H.A., van 't Klooster, J., Kruijt, M., Lindhout, W.H., Allen, C., Cai, X., Takken, F.L.W., de Jong, C.F., de Kock, M.J.D., Takken, F.L.W.; id_orcid, Westerink, N., Brandwagt, B.F., Vervoort, J.J.M.   +18 more
core   +1 more source

Limited impact of hepatitis A virus 3C protease-mediated cleavage on the functions of NEMO in human hepatocytes

Journal of Virology
NF-κB essential modulator (NEMO) is critically involved in the induction of interferons (IFNs) and pro-inflammatory cytokines. Hepatitis A virus (HAV) 3C protease was recently identified to cleave NEMO in non-hepatic cells.
Hao-En Huang, Ombretta Colasanti, Teng-Feng Li, Volker Lohmann   +3 more
doaj   +1 more source