Results 21 to 30 of about 3,268,667 (301)
Iterative Random Forests to detect predictive and stable high-order interactions [PDF]
, 2017 Genomics has revolutionized biology, enabling the interrogation of whole transcriptomes, genome-wide binding sites for proteins, and many other molecular processes.
Basu, Sumanta +3 more
core +2 more sources
Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-κB activation
Virology Journal, 2018 The cytoplasmic domain of lentiviral Envelopes (EnvCD) ensures Env incorporation into nascent virions and regulates Env trafficking to and from the plasma membrane.
Cyprien Beraud +2 more
doaj +1 more source
Molecular Interactions in Biofilms [PDF]
Chemistry & Biology, 2002 A biofilm may be defined as a microbially derived, sessile community characterized by cells that attach to an interface, embed in a matrix of exopolysaccharide, and demonstrate an altered phenotype. This review covers the current understanding of the nature of biofilms and the impact that molecular interactions may have on biofilm development and ...
Shirtliff, Mark E +2 more
openaire +2 more sources
MoMA-LigPath: A web server to simulate protein-ligand unbinding [PDF]
, 2013 Protein-ligand interactions taking place far away from the active site, during ligand binding or release, may determine molecular specificity and activity. However, obtaining information about these interactions with experimental or computational methods
Al-Bluwi +26 more
core +5 more sources
Molecular Force Fields with Gradient-Domain Machine Learning: Construction and Application to Dynamics of Small Molecules with Coupled Cluster Forces [PDF]
, 2019 We present the construction of molecular force fields for small molecules (less than 25 atoms) using the recently developed symmetrized gradient-domain machine learning (sGDML) approach [Chmiela et al., Nat. Commun. 9, 3887 (2018); Sci. Adv. 3, e1603015 (
Chmiela, Stefan +4 more
core +2 more sources
Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38
Nature Communications, 2020 The ATF2 transcription factor is phosphorylated by different mitogen-activated protein (MAP) kinases. Here, the authors show that the functionally distinct MAP kinases JNK and p38 control ATF2 through different binding sites and differential ...
Klára Kirsch +13 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2017 Temporal lobe epilepsy (TLE) is the most common type of focal epilepsy in humans, and is often developed after an initial precipitating brain injury. This form of epilepsy is frequently resistant to pharmacological treatment; therefore, the prevention of
Dmitry V. Amakhin +7 more
doaj +1 more source
Next-generation microbiology: from comparative genomics to gene function
Genome Biology, 2021 Microbiology is at a turning point in its 120-year history. Widespread next-generation sequencing has revealed genetic complexity among bacteria that could hardly have been imagined by pioneers such as Pasteur, Escherich and Koch.
Carolin M. Kobras +2 more
doaj +1 more source
Monte Carlo Simulation of a Model of Water [PDF]
, 2005 We simulate TIP3P water using a constrained Monte Carlo algorithm to generate electrostatic interactions eliminating the need to sum over long ranged Coulomb interactions.
Maggs, A. C.
core +2 more sources
Bio-Protocol, 2015 Fusarium pathogens are among the most damaging pathogens of cereals. These pathogens have the ability to attack the roots, seedlings, and flowering heads of barley and wheat plants (Simpson et al., 2004).
Shahin Ali +2 more
doaj +1 more source